SCHEMBL5707882

SCHEMBL5707882

CC(C)C(=O)OC(OC(=O)C(C)C)C(C)O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
TP53 P04637 1/20 0.32
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17928315 0.80 TSHR (0.35) TSHRELANE
SCHEMBL2989930 0.78 TSHR (0.33) TSHRTP53ELANE
SCHEMBL2989928 0.78 TSHR (0.33) TSHRTP53ELANE
SCHEMBL7994296 0.77
SCHEMBL28797211 0.77
SCHEMBL805312 0.77
SCHEMBL7810888 0.74 TSHR (0.55) TSHRTP53
Hydrochloric Acid SCHEMBL27396393 0.74 TSHR (0.35) TSHRTP53ELANE
SCHEMBL12390072 0.74 SMN1; SMN2 (0.36) TSHR
SCHEMBL19387352 0.74 SLC7A5 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10442884-B2 Dispersants with multiple aromatic imide anchor groups LUBRIZOL ADVANCED MATERIALS, INC. (US) 2019-10-15 US disclosed
EP-3063240-A1 DISPERSANT'S WITH MULTIPLE AROMATIC IMIDE ANCHOR GROUPS Lubrizol Advanced Materials, Inc. (US) 2016-09-07 EP disclosed
US-20160237196-A1 DISPERSANTS WITH MULTIPLE AROMATIC IMIDE ANCHOR GROUPS LUBRIZOL ADVANCED MAT INC (US) 2016-08-18 US disclosed
WO-2015066156-A1 DISPERSANT'S WITH MULTIPLE AROMATIC IMIDE ANCHOR GROUPS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2015-05-07 WO disclosed
WO-2015065829-A1 DISPERSANTS WITH MULTIPLE AROMATIC IMIDE ANCHOR GROUPS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2015-05-07 WO disclosed
EP-1089809-B2 POLYURETHANE DISPERSANTS LUBRIZOL CORP (US) 2013-11-13 EP disclosed
EP-1089809-B1 POLYURETHANE DISPERSANTS LUBRIZOL CORP (US) 2006-10-18 EP disclosed
US-6509409-B1 A dispersant comprising the addition product of a polyisocyanate having an average functionality of from 2 to 10 and one or more poly(oxyalkylene carbonyl) chains (POAC chain) such as those containing a POAC chain derived from AVECIA LIMITED (GB) 2003-01-21 US disclosed
EP-0956153-B1 DISPERSING AGENT EFKA ADDITIVES B V (NL) 2002-10-02 EP disclosed
EP-1089809-A1 POLYURETHANE DISPERSANTS Avecia Limited (GB) 2001-04-11 EP disclosed
EP-0956153-A1 DISPERSING AGENT Ekfa Chemicals B.V. (NL) 1999-11-17 EP disclosed
WO-1999056864-A1 POLYURETHANE DISPERSANTS AVECIA LIMITED (GB) 1999-11-11 WO disclosed
US-5882393-A REACTION PRODUCT OF POLYISOCYANATES WITH A COMPOUND OF RING STRUCTURE WITH AT LEAST ONE NITROGEN ATOM IN RING; LACQUER EFKA CHEMICALS B.V. (NL) 1999-03-16 US disclosed
WO-1997026984-A1 DISPERSING AGENT EKFA CHEMICALS B.V. (NL) 1997-07-31 WO disclosed