SCHEMBL19387352

SCHEMBL19387352

CC(C)C(=O)OC(OC(=O)[C@@H](N)C(C)C)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.41
DPP4 P27487 2/20 0.31
FAP Q12884 1/20 0.31
DPP8 Q6V1X1 1/20 0.31
DPP9 Q86TI2 1/20 0.31
DPP7 Q9UHL4 1/20 0.31
LAP3 P28838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17928315 0.86 TSHR (0.35)
SCHEMBL14887425 0.85 TSHR (0.41) SLC7A5DPP4FAPDPP8DPP9
SCHEMBL5987234 0.85 TSHR (0.41) SLC7A5DPP4FAPDPP8DPP9
SCHEMBL18823389 0.80 PRKCA (0.37) SLC7A5
SCHEMBL14884212 0.80 PRKCA (0.37) SLC7A5
SCHEMBL17833086 0.78 SLC7A5 (0.37) SLC7A5
SCHEMBL17833085 0.78 SLC7A5 (0.37) SLC7A5
SCHEMBL17833252 0.78 SLC7A5 (0.37) SLC7A5
SCHEMBL17833213 0.78 SLC7A5 (0.37) SLC7A5
SCHEMBL5987105 0.77 TSHR (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230183326-A1 PROTEIN-POLYMER-DRUG CONJUGATES ASANA BIOSCIENCES, LLC 2023-06-15 US disclosed
US-9770519-B2 Protein-polymer-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2017-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230183326-A1 PROTEIN-POLYMER-DRUG CONJUGATES PBRM1, STAMBP, TSPO SLC7A5 2258/4885DPP4 3823/4885FAP 1855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.