Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 11/20 | 0.66 |
| ▸ | GHSR | Q92847 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515850 | 0.89 | GPBAR1 (0.59) | GPBAR1POLBMEN1KMT2AGAA | |
| SCHEMBL3548012 | 0.87 | GPBAR1 (0.66) | GPBAR1GHSRPOLBNPC1MEN1 | |
| SCHEMBL1575050 | 0.87 | GPBAR1 (0.66) | GPBAR1GHSRPOLBNPC1MEN1 | |
| SCHEMBL3068021 | 0.86 | GPBAR1 (0.61) | GPBAR1NPC1MEN1KMT2AGAA | |
| SCHEMBL892042 | 0.85 | KMT2A (0.71) | GPBAR1POLBNPC1MEN1KMT2A | |
| SCHEMBL11518716 | 0.83 | GPBAR1 (0.48) | GPBAR1MEN1KMT2AMAPTGAA | |
| SCHEMBL11419174 | 0.83 | GPBAR1 (0.61) | GPBAR1GHSRPOLBNPC1MEN1 | |
| SCHEMBL3546359 | 0.83 | GPBAR1 (0.78) | GPBAR1GHSRPOLBNPC1 | |
| SCHEMBL2723582 | 0.83 | GPBAR1 (0.62) | GPBAR1POLBMEN1KMT2AMAPT | |
| SCHEMBL11517320 | 0.82 | GPBAR1 (0.66) | GPBAR1GHSRPOLBNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706387-A1 | SUBSTITUTED HETEROCYCLIC AMIDES HAVING A FUNGICIDAL EFFECT | Bayer CropScience Aktiengesellschaft (DE) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005066138-A1 | SUBSTITUTED HETEROCYCLIC AMIDES HAVING A FUNGICIDAL EFFECT | BAYER CROPSCIENCE AG (DE) | 2005-07-21 | — | — | WO | disclosed |
| US-4155905-A | 6-Substituted penicillanic acid and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1979-05-22 | — | — | US | disclosed |
| US-4077967-A | 6-Substituted penicillanic acid and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4061851-A | 7-Amino-7-arylthio cephalosporins | E. R. SQUIBB & SONS, INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4061629-A | 6-Amino-6-arylthio penicillanic acids and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4029669-A | 6-Benzalimino-6-arylthio penicillanic acids and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1977-06-14 | — | — | US | disclosed |
| US-4026886-A | 7-Acyl-7-arylthiocephalosporins | E. R. SQUIBB & SONS, INC. (US) | 1977-05-31 | — | — | US | disclosed |
| US-3965093-A | 6-Arylthio penicillanic acid and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3954744-A | ANTIBACTERIAL | E. R. SQUIBB & SONS, INC. (US) | 1976-05-04 | — | — | US | disclosed |