SCHEMBL892042

SCHEMBL892042

Cc1onc(-c2ccccc2)c1C(=O)Cl

nearest known ligand 0.71

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.71
MEN1 O00255 1/20 0.71
GAA P10253 1/20 0.71
TSHR P16473 4/20 0.59
POLB P06746 3/20 0.59
HTT P42858 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
LMNA P02545 1/20 0.59
GPBAR1 Q8TDU6 1/20 0.59
MAPK1 P28482 2/20 0.58
USP2 O75604 1/20 0.58
ALDH1A1 P00352 2/20 0.57
ALOX15 P16050 1/20 0.57
NPC1 O15118 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11515850 0.87 GPBAR1 (0.59) KMT2AMEN1GAATSHRPOLB
SCHEMBL27722453 0.86 KMT2A (0.76) KMT2AMEN1GAATSHRPOLB
SCHEMBL316093 0.86 KMT2A (0.76) KMT2AMEN1GAATSHRPOLB
SCHEMBL5708155 0.85 GPBAR1 (0.66) KMT2AMEN1GAATSHRPOLB
SCHEMBL1574735 0.85 KMT2A (0.73) KMT2AMEN1GAATSHRPOLB
Hydrochloric Acid SCHEMBL4846563 0.85 KMT2A (0.73) KMT2AMEN1GAATSHRPOLB
SCHEMBL3068021 0.84 GPBAR1 (0.61) KMT2AMEN1GAATSHRLMNA
SCHEMBL10929681 0.83 KMT2A (0.71) KMT2AMEN1GAATSHRPOLB
SCHEMBL903110 0.83 KMT2A (1.00) KMT2AMEN1GAATSHRPOLB
SCHEMBL7608812 0.83 KMT2A (0.71) KMT2AMEN1GAATSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118772476-B High-strength base film for composite current collector and preparation method thereof 扬州博恒新能源材料科技有限公司 2024-11-29 CN claimed
CN-118772476-A High-strength base film for composite current collector and preparation method thereof 扬州博恒新能源材料科技有限公司 2024-10-15 CN claimed
CN-116514839-A Synthesis method of oxacillin sodium 国药集团威奇达药业有限公司 2023-08-01 CN claimed
CN-1233634-C Chemical synthesis method of 3-phenyl-5-methylisoxazole-4-formyl chloride UNIV ZHEJIANG POLYTECHNIC (CN) 2005-12-28 CN claimed
CN-1535959-A Chemical synthesis method of 3-phenyl-5-methylisoxazole-4-formyl chloride 浙江工业大学 2004-10-13 CN claimed
EP-0140949-A1 NOVEL CEPHALOSPORIN DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, THEIR USE IN THERAPY AS ANTIBIOTICS AND A PROCESS FOR THE PREPARATION OF THE NOVEL COMPOUNDS BIOGAL GYOGYSZERGYAR (HU) 1985-05-15 EP claimed
WO-1984004096-A1 NOVEL CEPHALOSPORIN DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, THEIR USE IN THERAPY AS ANTIBIOTICS AND A PROCESS FOR THE PREPARATION OF THE NOVEL COMPOUNDS BIOGAL GYOGYSZERGYAR (HU) 1984-10-25 WO claimed
CN-121181573-B Cephalosporium containing C-3 tetrahydrofuran derivative and application thereof 重庆汉佩生物科技有限公司 2026-02-27 CN disclosed
CN-116514839-B Synthesis method of oxacillin sodium 国药集团威奇达药业有限公司 2025-08-12 CN disclosed
US-20240425491-A1 HETEROARYL COMPOUNDS USEFUL IN THE TREATMENT OF COGNITIVE DISORDERS DRAIG THERAPEUTICS LTD (GB) 2024-12-26 US disclosed
CN-118772476-B High-strength base film for composite current collector and preparation method thereof 扬州博恒新能源材料科技有限公司 2024-11-29 CN disclosed
CN-118772476-B High-strength base film for composite current collector and preparation method thereof 扬州博恒新能源材料科技有限公司 2024-11-29 CN disclosed
CN-118772476-A High-strength base film for composite current collector and preparation method thereof 扬州博恒新能源材料科技有限公司 2024-10-15 CN disclosed
US-4145343-A BACTERICIDES UCB SOCIETE ANONYME (BE) 1979-03-20 US disclosed
US-4143039-A ANTIBACTERIAL 3-(5-TETRAZOLYL)PENAM COMPOUNDS PFIZER INC. (US) 1979-03-06 US disclosed
US-4139628-A ANTIBIOTICS U C B, SOCIETE ANONYME (BE) 1979-02-13 US disclosed
US-4137236-A ANTIBIOTICS, BACTERICIDES U C B, SOCIETE ANONYME (BE) 1979-01-30 US disclosed
US-4115385-A PENICILLINS PFIZER INC. (US) 1978-09-19 US disclosed
US-4061628-A Intermediates for producing semi-synthetic penicillins and cephalosporins and methods of production AMERICAN HOME PRODUCTS CORPORATION (US) 1977-12-06 US disclosed
US-3997532-A Intermediates for producing semi-synthetic cephalosporins AMERICAN HOME PRODUCTS CORPORATION (US) 1976-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425491-A1 HETEROARYL COMPOUNDS USEFUL IN THE TREATMENT OF COGNITIVE DISORDERS GABRA5, GABRB3, GABRA3 KMT2A 3453/4885MEN1 4676/4885GAA 1976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.