Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708553 | 0.87 | KMT2A (0.45) | KMT2ACYP2C9CYP2C19CYP1A2MEN1 | |
| SCHEMBL5708507 | 0.85 | KMT2A (0.48) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5708565 | 0.84 | KMT2A (0.60) | KMT2ACYP2C9CYP2C19CYP1A2MEN1 | |
| SCHEMBL5708543 | 0.80 | ALDH1A1 (0.37) | KMT2ACYP2C9CYP2C19CYP1A2MEN1 | |
| SCHEMBL5283318 | 0.77 | KMT2A (0.40) | KMT2ACYP2C9CYP2C19CYP1A2MEN1 | |
| SCHEMBL5279506 | 0.77 | KMT2A (0.40) | KMT2ACYP2C9CYP2C19CYP1A2MEN1 | |
| SCHEMBL4617247 | 0.76 | ALDH1A1 (0.54) | KMT2ACYP2C9CYP2C19CYP1A2MEN1 | |
| SCHEMBL4617250 | 0.76 | ALDH1A1 (0.54) | KMT2ACYP2C9CYP2C19CYP1A2MEN1 | |
| SCHEMBL5708469 | 0.75 | RXFP1 (0.57) | KMT2AMEN1 | |
| SCHEMBL4615745 | 0.70 | GSK3B (0.47) | KMT2ACYP2C9CYP2C19CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599179-B1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2006-10-11 | — | — | EP | claimed |