Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 3/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29126352 | 0.95 | SLC1A1 (0.39) | SLC1A1SLC1A3SLC1A2GRM8GRM6 | |
| SCHEMBL404448 | 0.95 | SLC1A1 (0.39) | SLC1A1SLC1A3SLC1A2GRM8GRM6 | |
| SCHEMBL16735413 | 0.93 | SLC1A1 (0.38) | SLC1A1SLC1A3SLC1A2GRM8GRM6 | |
| SCHEMBL16735414 | 0.93 | SLC1A1 (0.38) | SLC1A1SLC1A3SLC1A2GRM8GRM6 | |
| Ammonia Solution, Strong SCHEMBL16735417 | 0.90 | SLC1A1 (0.38) | SLC1A1SLC1A3SLC1A2GRM8GRM6 | |
| Ammonia Solution, Strong SCHEMBL16735418 | 0.90 | SLC1A1 (0.38) | SLC1A1SLC1A3SLC1A2GRM8GRM6 | |
| SCHEMBL4904802 | 0.81 | SLC1A1 (0.42) | SLC1A1SLC1A3SLC1A2GRM8GRM6 | |
| SCHEMBL710039 | 0.81 | SLC1A1 (0.42) | SLC1A1SLC1A3SLC1A2GRM8GRM6 | |
| SCHEMBL710038 | 0.81 | SLC1A1 (0.56) | SLC1A1SLC1A3SLC1A2GRM8GRM6 | |
| SCHEMBL28138215 | 0.80 | SLC1A1 (0.41) | SLC1A1SLC1A3SLC1A2GRM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1726688-A1 | Cerium ion-containing solution and corrosion inhibitor | Shin-Etsu Chemical Co., Ltd. (JP) | 2006-11-29 | — | — | EP | claimed |
| US-20060261313-A1 | Cerium ion-containing solution and corrosion inhibitor | SHIN-ETSU CHEMICAL CO., LTD. | 2006-11-23 | — | — | US | claimed |
| EP-1726688-A1 | Cerium ion-containing solution and corrosion inhibitor | Shin-Etsu Chemical Co., Ltd. (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-20060261313-A1 | Cerium ion-containing solution and corrosion inhibitor | SHIN-ETSU CHEMICAL CO., LTD. | 2006-11-23 | — | — | US | disclosed |