⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13349763 | 0.73 | TP53 (0.32) | — | |
| SCHEMBL8047574 | 0.73 | TP53 (0.32) | — | |
| SCHEMBL3381973 | 0.73 | TP53 (0.32) | — | |
| SCHEMBL8583750 | 0.63 | — | — | |
| SCHEMBL2698215 | 0.63 | KDM4E (0.37) | — | |
| SCHEMBL4353223 | 0.58 | — | — | |
| SCHEMBL911568 | 0.56 | TP53 (0.50) | — | |
| SCHEMBL910568 | 0.56 | TP53 (0.50) | — | |
| SCHEMBL12172563 | 0.54 | TP53 (0.48) | — | |
| SCHEMBL19557679 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999209-B1 | 2-SULFAMOYLBENZOIC ACID DERIVATIVES | KAKEN PHARMA CO LTD (JP) | 2006-11-02 | — | — | EP | disclosed |
| US-20020049228-A1 | 2-Sulfamoylbenzoic acid derivatives | KAKEN PHARMACEUTICALS | 2002-04-25 | — | — | US | disclosed |
| US-6376671-B1 | LEUKOTRIENE AND THROMBOXANE A2 ANTAGONISTIC AGENTS; ANTIALLERGIC AGENTS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-6255321-B1 | ANTIALLERGENS; RESPIRATRORY SYSTEM DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0999209-A1 | 2-SULFAMOYLBENZOIC ACID DERIVATIVES | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2000-05-10 | — | — | EP | disclosed |