Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | PPM1B | O75688 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.50 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.50 |
| ▸ | PPP5C | P53041 | 1/20 | 0.50 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.50 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL911568 | 1.00 | TP53 (0.50) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL18951250 | 0.92 | TP53 (0.48) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL18785025 | 0.92 | TP53 (0.48) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL12172563 | 0.92 | TP53 (0.48) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL19600897 | 0.82 | TP53 (0.36) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL17249827 | 0.82 | TP53 (0.41) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL20132626 | 0.76 | TP53 (0.36) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL17249830 | 0.75 | TP53 (0.44) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL15358750 | 0.74 | TP53 (0.35) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL11757446 | 0.74 | TP53 (0.46) | TP53CYP3A4MAPK1HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1813592-B1 | CAGE-SHAPED CYCLOBUTANOIC DIANHYDRIDES AND PROCESS FOR PRODUCTION THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2012-10-10 | — | — | EP | disclosed |
| US-7872148-B2 | Cage-shaped cyclobutanoic dianhydrides and process for production thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-7872148-B2 | Cage-shaped cyclobutanoic dianhydrides and process for production thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20100063243-A1 | POLYAMIC ACIDS, POLYIMIDES, AND PROCESSES FOR THE PRODUCTION THEREOF | NISSAN CHEMICAL INDUSTRIES LTD (JP) | 2010-03-11 | — | — | US | disclosed |
| US-20090012318-A1 | Cage-shaped cyclobutanoic dianhydrides and process for production thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-01-08 | — | — | US | disclosed |
| US-20090012318-A1 | Cage-shaped cyclobutanoic dianhydrides and process for production thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-1813592-A1 | CAGE-SHAPED CYCLOBUTANOIC DIANHYDRIDES AND PROCESS FOR PRODUCTION THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012318-A1 | Cage-shaped cyclobutanoic dianhydrides and process for production thereof | ADH1C, ADH1A, ADH5 | TP53 3202/4885CYP3A4 570/4885MAPK1 3362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.