Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6102970 | 0.89 | NPC1 (0.53) | SMN1; SMN2MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL5708803 | 0.89 | NPC1 (0.53) | SMN1; SMN2MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL5708795 | 0.89 | KMT2A (0.65) | SMN1; SMN2MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL5708762 | 0.89 | NPC1 (0.68) | SMN1; SMN2MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL6102910 | 0.87 | KMT2A (0.60) | SMN1; SMN2MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL5708871 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL5708842 | 0.86 | MEN1 (0.50) | SMN1; SMN2MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL5708770 | 0.86 | MEN1 (0.50) | SMN1; SMN2MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL5708915 | 0.84 | KMT2A (0.48) | SMN1; SMN2MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL5708964 | 0.84 | MAPT (0.53) | SMN1; SMN2MEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708999-A1 | BRONCHORELAXING COMPOUNDS | RESPIRATORIUS AB (SE) | 2006-10-11 | — | — | EP | disclosed |
| US-20060040919-A1 | Bronchorelaxing compounds | RESPIRATORIUS AB (SE) | 2006-02-23 | — | — | US | disclosed |
| WO-2005070887-A1 | BRONCHORELAXING COMPOUNDS | RESPIRATORIUS AB (SE) | 2005-08-04 | — | — | WO | disclosed |
| US-20050165004-A1 | Bronchorelaxing compounds | RESPIRATORIUS AB (SE) | 2005-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165004-A1 | Bronchorelaxing compounds | GPR6, CHRM3, NR1H3 | SMN1; SMN2 2872/4885MEN1 1409/4885KMT2A 3030/4885 |
| US-20060040919-A1 | Bronchorelaxing compounds | CHRM3, GPR3, CHRM2 | SMN1; SMN2 2618/4885MEN1 2210/4885KMT2A 3875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.