SCHEMBL5709148

SCHEMBL5709148

CC1=Cc2c(-c3ccccc3)cccc2C1[Hf](C)C

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.34
CD274 Q9NZQ7 1/20 0.34
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
BRD4 O60885 1/20 0.31
HTR1A P08908 2/20 0.31
HTR7 P34969 2/20 0.31
DRD2 P14416 1/20 0.31
DRD1 P21728 1/20 0.31
USP30 Q70CQ3 1/20 0.30
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
CYP2A6 P11509 1/20 0.30
CYP2B6 P20813 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5189632 0.86 PDCD1 (0.38) PDCD1CD274CHRNB2CHRNA4HTR7
SCHEMBL4079021 0.86 PDCD1 (0.33) PDCD1CD274CHRNB2CHRNA4BRD4
Hydrochloric Acid SCHEMBL2114855 0.84 PDCD1 (0.33) PDCD1CD274CHRNB2CHRNA4BRD4
SCHEMBL28438823 0.84 CHRNB2 (0.33) PDCD1CD274CHRNB2CHRNA4BRD4
SCHEMBL29556985 0.83 PDCD1 (0.32) PDCD1CD274CHRNB2CHRNA4HTR1A
SCHEMBL8903129 0.83 PDCD1 (0.32) PDCD1CD274CHRNB2CHRNA4USP30
SCHEMBL8194343 0.83 PDCD1 (0.35) PDCD1CD274CHRNB2CHRNA4HTR1A
SCHEMBL2234118 0.83 PDCD1 (0.32) PDCD1CD274CHRNB2CHRNA4HTR1A
Hydrochloric Acid SCHEMBL7646524 0.82 PDCD1 (0.31) PDCD1CD274CHRNB2CHRNA4USP30
Hydrochloric Acid SCHEMBL1201256 0.82 PDCD1 (0.31) PDCD1CD274CHRNB2CHRNA4USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1705688-A Multi-catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEM PATENTS INC (US) 2005-12-07 CN claimed
EP-1709085-A2 SUPPORTED ACTIVATOR ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2006-10-11 EP disclosed
CN-1705688-A Multi-catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEM PATENTS INC (US) 2005-12-07 CN disclosed
WO-2005068515-A2 SUPPORTED ACTIVATOR FOR POLYMERISATION EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2005-07-28 WO disclosed
CN-1178960-C Siloxy substituted cocatalyst activators for olefin polymerization 埃克森美孚化学专利公司 2004-12-08 CN disclosed
CN-1437607-A Siloxy substituted cocatalyst activators for olefin polymerization EXXONMOBIL CHEM PATENTS INC (US) 2003-08-20 CN disclosed