SCHEMBL5709182

SCHEMBL5709182

CC1=Cc2c(-c3ccccc3)cccc2C1[Zr](C)C

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.34
CD274 Q9NZQ7 1/20 0.34
BRD4 O60885 1/20 0.34
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
HTR2B P41595 3/20 0.32
TMEM97 Q5BJF2 3/20 0.32
HTR1A P08908 2/20 0.32
HTR7 P34969 2/20 0.32
SIGMAR1 Q99720 2/20 0.32
USP30 Q70CQ3 1/20 0.30
CYP2A6 P11509 1/20 0.30
CYP2B6 P20813 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27670432 0.89 EDNRB (0.32)
SCHEMBL3163967 0.86 BRD4 (0.33) PDCD1CD274BRD4CHRNB2CHRNA4
SCHEMBL7930455 0.86 BRD4 (0.33) PDCD1CD274BRD4CHRNB2CHRNA4
SCHEMBL8678769 0.84 BRD4 (0.33) PDCD1CD274BRD4CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL8168468 0.84 BRD4 (0.33) PDCD1CD274BRD4CHRNB2CHRNA4
SCHEMBL27670433 0.84 EDNRB (0.35)
SCHEMBL2152789 0.83 BRD4 (0.32) PDCD1CD274BRD4CHRNB2CHRNA4
SCHEMBL215863 0.83 BRD4 (0.32) PDCD1CD274BRD4CHRNB2CHRNA4
SCHEMBL8415755 0.83 BRD4 (0.32) PDCD1CD274BRD4CHRNB2CHRNA4
SCHEMBL7209110 0.83 PDCD1 (0.35) PDCD1CD274BRD4CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101765461-B Preparation of activating support TOTAL PETROCHEMICALS RES FELUY 2012-09-05 CN claimed
CN-1705688-A Multi-catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEM PATENTS INC (US) 2005-12-07 CN claimed
CN-117616055-A Polyethylene copolymers with broad short chain branching distribution 格雷斯公司 2024-02-27 CN disclosed
CN-111868106-B Catalyst system and process for poly-alpha-olefins having high vinylidene content 埃克森美孚化学专利公司 2023-02-17 CN disclosed
CN-114845980-A Dimer-selective metallocene catalyst, non-aromatic hydrocarbon soluble activator and method for preparing poly alpha-olefin oligomer using the same 埃克森美孚化学专利公司 2022-08-02 CN disclosed
CN-114502521-A Process for producing low viscosity polyalphaolefins using non-aromatic hydrocarbon soluble activators 埃克森美孚化学专利公司 2022-05-13 CN disclosed
CN-113039221-A Process for preparing poly-alpha-olefin terpolymer 埃克森美孚化学专利公司 2021-06-25 CN disclosed
CN-113015755-A Metallocene dimer selective catalyst and process for preparing poly-alpha-olefin dimers 埃克森美孚化学专利公司 2021-06-22 CN disclosed
CN-112912357-A Process and apparatus for producing poly-alpha-olefin terpolymer 埃克森美孚化学专利公司 2021-06-04 CN disclosed
CN-111868106-A Catalyst system and process for poly-alpha-olefins having high vinylidene content 埃克森美孚化学专利公司 2020-10-30 CN disclosed
CN-109666089-A A kind of preparation method and catalyst of load metallocene catalyst 中国石油化工股份有限公司 2019-04-23 CN disclosed
EP-0923609-A1 INCORPORATION OF FREE RADICAL INHIBITORS IN POLYOLEFINS THE DOW CHEMICAL COMPANY (US) 1999-06-23 EP disclosed
CN-1217685-A VULCANIZED MOLDING HAVING SURFACE DECORATIVE LAYER, PAINTED THERMOPLASTIC RESIN COMPOSITION AND PAINTED ELASTOMER COMPOSITION MITSUI CHEMICALS INC (JP) 1999-05-26 CN disclosed
CN-1216053-A SHRINKABLE FILM MADE FROM OLEFINE COPOLYMER MITSUI CHEMICALS INC (JP) 1999-05-05 CN disclosed
CN-1216055-A RUBBER COMPOSITIONS FOR TIRES MITSUI CHEMICALS INC (JP) 1999-05-05 CN disclosed
EP-0891381-A1 OLEFIN SOLUTION POLYMERIZATION THE DOW CHEMICAL COMPANY (US) 1999-01-20 EP disclosed
US-5807936-A Transition metal compound TARGOR GMBH (DE) 1998-09-15 US disclosed
WO-1998009995-A1 INCORPORATION OF FREE RADICAL INHIBITORS IN POLYOLEFINS THE DOW CHEMICAL COMPANY (US) 1998-03-12 WO disclosed
WO-1997049738-A1 INCORPORATION OF FUNCTIONALIZED COMONOMERS IN POLYOLEFINS THE DOW CHEMICAL COMPANY (US) 1997-12-31 WO disclosed
WO-1997036942-A1 OLEFIN SOLUTION POLYMERIZATION THE DOW CHEMICAL COMPANY (US) 1997-10-09 WO disclosed