SCHEMBL215863

SCHEMBL215863

CC1=Cc2c(-c3ccccc3)cccc2C1[Zr](C1C(C)=Cc2c(-c3ccccc3)cccc21)[SiH](C)C

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.32
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31
HTR1A P08908 1/20 0.30
HTR7 P34969 1/20 0.30
HTR2B P41595 1/20 0.30
TMEM97 Q5BJF2 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29442977 1.00 BRD4 (0.32) BRD4PDCD1CD274CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL819254 0.99 BRD4 (0.31) BRD4PDCD1CD274CHRNB2CHRNA4
SCHEMBL5363333 0.97 BRD4 (0.31) BRD4PDCD1CD274
SCHEMBL5360910 0.94 BRD4 (0.31) BRD4PDCD1CD274
SCHEMBL1531658 0.93 HTR1A (0.30) HTR1AHTR7HTR2BTMEM97SIGMAR1
SCHEMBL9069407 0.93
SCHEMBL61921 0.90 MAOB (0.33)
SCHEMBL2234309 0.90 EDNRB (0.30)
Hydrochloric Acid SCHEMBL2234623 0.89
SCHEMBL5351378 0.87 ENPP3 (0.33) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 423 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528892-B2 Alkylation of transition metal coordination catalyst complexes EXXONMOBIL CHEMICAL PATENTS INC. (US) 2026-01-20 US claimed
US-12503529-B2 Polymers of 4-substituted hexadiene and processes for production thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2025-12-23 US claimed
US-20230357454-A1 Methods for Delivery of Non-Aromatic Solutions to Polymerization Reactors EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-11-09 US claimed
EP-4192888-A1 METHODS FOR DELIVERY OF NON-AROMATIC SOLUTIONS TO POLYMERIZATION REACTORS ExxonMobil Chemical Patents Inc. (US) 2023-06-14 EP claimed
US-20230141606-A1 Alkylation of Transition Metal Coordination Catalyst Complexes EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-05-11 US claimed
US-20220289879-A1 Polymers of 4-Substituted Hexadiene and Processes for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2022-09-15 US claimed
EP-3119817-B1 PROCESS TO PRODUCE ETHYLENE PROPYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-09-30 EP claimed
EP-3037437-A1 Process for the preparation of a polyolefin having one or multiple end-functionalized branches. SABIC Global Technologies B.V. (NL) 2016-06-29 EP claimed
EP-2591011-B1 MULTI-COMPONENT CATALYST SYSTEMS AND POLYMERIZATION PROCESSES FOR FORMING BROAD COMPOSITION DISTRIBUTION POLYMERS FINA TECHNOLOGY (US) 2016-04-06 EP claimed
EP-2183287-B1 TRANSITION METAL CATALYSTS AND FORMATION THEREOF FINA TECHNOLOGY (US) 2016-02-24 EP claimed
WO-1999046270-A1 INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1999-09-16 WO claimed
EP-0775148-B1 BISCYCLOPENTADIENYL DIENE COMPLEXES DOW CHEMICAL CO (US) 1999-08-25 EP claimed
EP-0785956-B1 POLYMERIZATION CATALYST SYSTEMS, THEIR PRODUCTION AND USE EXXON CHEMICAL PATENTS INC (US) 1999-04-28 EP claimed
EP-0889911-A1 METALLOCENE COCATALYST THE DOW CHEMICAL COMPANY (US) 1999-01-13 EP claimed
EP-0758355-B1 APPLICATIONS OF ISOTACTIC POLYPROPYLENE, PROCESSES AND PRODUCTS THEREOF EXXON CHEMICAL PATENTS INC (US) 1998-12-09 EP claimed
EP-0705281-B1 SUPPORTED METALLOCENE CATALYST SYSTEMS FOR THE POLYMERIZATION OF OLEFINS, PREPARATION AND USE THEREOF EXXON CHEMICAL PATENTS INC (US) 1998-03-11 EP claimed
WO-1997036937-A1 METALLOCENE COCATALYST THE DOW CHEMICAL COMPANY (US) 1997-10-09 WO claimed
EP-0775148-A1 BISCYCLOPENTADIENYL DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1997-05-28 EP claimed
US-5616664-A Polymerization process with biscyclopentadienyl diene complex containing catalysts THE DOW CHEMICAL COMPANY (US) 1997-04-01 US claimed
WO-1996004290-A1 BISCYCLOPENTADIENYL DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1996-02-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528892-B2 Alkylation of transition metal coordination catalyst complexes LEF1, TAF1, FLI1 BRD4 2685/4885PDCD1 80/4885CD274 195/4885
US-20230141606-A1 Alkylation of Transition Metal Coordination Catalyst Complexes AS3MT, AP1M1, AP3M1 BRD4 1773/4885PDCD1 980/4885CD274 842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.