Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HRAS | P01112 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12582112 | 0.82 | ATM (0.40) | HDAC8ATMTRIM24TRIM33 | |
| SCHEMBL18558714 | 0.76 | ATM (0.43) | HDAC8ATMKDM4EMAPTALDH1A1 | |
| SCHEMBL2072144 | 0.74 | HDAC8 (0.58) | HDAC8ATMKDM4EMAPTTRIM24 | |
| SCHEMBL28223520 | 0.73 | HRAS (0.36) | HRASESR1TOP1ESR2KDM4E | |
| SCHEMBL5709196 | 0.73 | HRAS (0.36) | HRASESR1TOP1ESR2KDM4E | |
| SCHEMBL13257099 | 0.73 | ATM (0.35) | HDAC8ATMTRIM24TRIM33 | |
| SCHEMBL4855585 | 0.72 | HRAS (0.50) | HDAC8HRASESR1TOP1ESR2 | |
| SCHEMBL4850168 | 0.71 | HRAS (0.49) | HDAC8HRASESR1TOP1ESR2 | |
| SCHEMBL16271028 | 0.70 | — | — | |
| SCHEMBL5400147 | 0.69 | ATM (0.40) | HDAC8ATMTRIM24TRIM33ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641753-B1 | PROCESS FOR THE SYNTHESIS OF DISTAMYCIN AND DERIVATIVES THEREOF USING 1-METHYL-4-FORMYLAMINO-2-PYRROLECARBONYL CHLORIDE ITERATIVELY AS AN INTERMEDIATE | NAXOSPHARMA S R L (IT) | 2006-10-18 | — | — | EP | claimed |