SCHEMBL5709283

SCHEMBL5709283

Oc1ccc(C(Br)c2ccc(O)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.55
ESR2 Q92731 8/20 0.55
PDCD1 Q15116 1/20 0.52
CD274 Q9NZQ7 1/20 0.52
ALOX15 P16050 4/20 0.52
LMNA P02545 2/20 0.52
CYP3A4 P08684 2/20 0.52
MAPT P10636 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
CYP1A2 P05177 1/20 0.52
PGR P06401 1/20 0.52
CHRM2 P08172 1/20 0.52
ADORA3 P0DMS8 1/20 0.52
AR P10275 1/20 0.52
CYP2D6 P10635 1/20 0.52
CHRM1 P11229 1/20 0.52
CYP2C9 P11712 1/20 0.52
DRD1 P21728 1/20 0.52
TBXA2R P21731 1/20 0.52
PTGS1 P23219 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7300588 0.81 ESR1 (0.55) ESR1ESR2PDCD1CD274ALOX15
SCHEMBL11510796 0.77 ESR1 (0.50) ESR1ESR2PDCD1CD274ALOX15
SCHEMBL677922 0.77 ESR1 (0.62) ESR1ESR2PDCD1CD274ALOX15
SCHEMBL9181985 0.75 ESR1 (0.55) ESR1ESR2PDCD1CD274ALOX15
SCHEMBL31274990 0.73 ESR1 (0.58) ESR1ESR2PDCD1CD274ALOX15
SCHEMBL216712 0.73 ESR1 (0.58) ESR1ESR2PDCD1CD274ALOX15
SCHEMBL133408 0.73 ESR1 (0.58) ESR1ESR2PDCD1CD274ALOX15
SCHEMBL40254 0.73 ESR1 (0.58) ESR1ESR2PDCD1CD274ALOX15
SCHEMBL9222812 0.73 ESR1 (0.52) ESR1ESR2PDCD1CD274ALOX15
SCHEMBL10915629 0.73 ESR1 (0.50) ESR1ESR2PDCD1CD274ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1711546-A1 LOW-VISCOSITY SOLUTIONS OF TDI-ISOCYANURATES IN BRANCHED DIALKYLPHTHALATES, WITH A LOW MONOMER CONTENT Lanxess Deutschland GmbH (DE) 2006-10-18 EP disclosed
WO-2005070984-A1 LOW-VISCOSITY SOLUTIONS OF TDI-ISOCYANURATES IN BRANCHED DIALKYLPHTHALATES, WITH A LOW MONOMER CONTENT LANXESS DEUTSCHLAND GMBH (DE) 2005-08-04 WO disclosed