Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709365 | 0.81 | SRD5A1 (0.45) | CYP3A4CYP17A1CYP11B2CYP11B1SLC6A2 | |
| SCHEMBL15679221 | 0.81 | KDM1A (0.48) | SLC6A2SLC6A4KDM1A | |
| SCHEMBL5709402 | 0.79 | CYP17A1 (0.46) | CYP3A4CYP17A1CYP11B2CYP11B1SLC6A2 | |
| SCHEMBL5709468 | 0.75 | SLC6A4 (0.41) | CYP3A4CYP17A1CYP11B2CYP11B1SLC6A2 | |
| SCHEMBL5709417 | 0.74 | PRCP (0.56) | SLC6A2SLC6A4SLC6A3 | |
| Alcohol SCHEMBL27680722 | 0.73 | CYP3A4 (0.50) | CYP3A4CYP17A1CYP11B2CYP11B1SLC6A2 | |
| SCHEMBL27680731 | 0.72 | TRPM5 (0.47) | SLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL8528885 | 0.72 | ESR1 (0.45) | CYP3A4CYP17A1CYP11B2CYP11B1KDM1A | |
| SCHEMBL5709325 | 0.72 | CA1 (0.54) | SLC6A2SLC6A4SLC6A3KDM1ACA1 | |
| SCHEMBL24899246 | 0.71 | KDM1A (0.49) | CYP3A4CYP17A1CYP11B2CYP11B1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1950328-A | Phenyl indan derivatives | LUNDBECK & CO AS H (DK) | 2007-04-18 | — | — | CN | disclosed |
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |