Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7157450 | 0.94 | NAAA (0.60) | NAAACA2MAPTL3MBTL1HDAC3 | |
| SCHEMBL5694739 | 0.89 | NAAA (0.53) | NAAACA2L3MBTL1HDAC3HDAC4 | |
| SCHEMBL5539564 | 0.89 | NAAA (0.53) | NAAACA2L3MBTL1HDAC3HDAC4 | |
| SCHEMBL14599479 | 0.89 | NAAA (0.53) | NAAACA2L3MBTL1HDAC3HDAC4 | |
| SCHEMBL5709548 | 0.87 | APP (0.53) | NAAACA2L3MBTL1HDAC3HDAC4 | |
| SCHEMBL5543338 | 0.87 | APP (0.53) | NAAACA2L3MBTL1HDAC3HDAC4 | |
| SCHEMBL5694756 | 0.87 | APP (0.53) | NAAACA2L3MBTL1HDAC3HDAC4 | |
| SCHEMBL5694738 | 0.87 | NAAA (0.57) | NAAACA2MAPTL3MBTL1APP | |
| SCHEMBL7158417 | 0.85 | NAAA (0.53) | NAAAMEN1GAAMAPTKMT2A | |
| SCHEMBL5694741 | 0.85 | NAAA (0.55) | NAAACA2MAPTL3MBTL1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060231589-A1 | Hydroxynaphthalenedicarboxylic acid hydrazide and derivatives thereof as well as process for preparing them | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO | 2006-10-19 | — | — | US | disclosed |
| EP-1712546-A1 | Hydroxynaphthalenedicarboxylic acid hydrazide and derivatives thereof as well as process for preparing them | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2006-10-18 | — | — | EP | disclosed |