Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | STS | P08842 | 7/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3914093 | 0.92 | ESR1 (0.50) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL3914575 | 0.92 | ESR1 (0.56) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL3915303 | 0.91 | ESR1 (0.55) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL3915308 | 0.91 | ESR1 (0.55) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL3922394 | 0.91 | ESR1 (0.49) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL3913997 | 0.91 | STS (0.55) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL3922390 | 0.91 | ESR1 (0.49) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL6665452 | 0.88 | ESR1 (0.52) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL14599483 | 0.87 | ESR1 (0.54) | ESR1STS | |
| SCHEMBL8487058 | 0.87 | ESR1 (0.54) | ESR1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060231589-A1 | Hydroxynaphthalenedicarboxylic acid hydrazide and derivatives thereof as well as process for preparing them | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO | 2006-10-19 | — | — | US | disclosed |
| EP-1712546-A1 | Hydroxynaphthalenedicarboxylic acid hydrazide and derivatives thereof as well as process for preparing them | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2006-10-18 | — | — | EP | disclosed |