Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | STS | P08842 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3915308 | 0.99 | ESR1 (0.55) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL6665452 | 0.96 | ESR1 (0.52) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL8487058 | 0.95 | ESR1 (0.54) | ESR1STSCNR2 | |
| SCHEMBL14599483 | 0.95 | ESR1 (0.54) | ESR1STSCNR2 | |
| SCHEMBL5709555 | 0.92 | ESR1 (0.59) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL3914093 | 0.90 | ESR1 (0.50) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL3915303 | 0.89 | ESR1 (0.55) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL3913997 | 0.89 | STS (0.55) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL3922394 | 0.89 | ESR1 (0.49) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL3918302 | 0.87 | CA12 (0.56) | ESR1LMNASTSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531691-B2 | Method for producing naphthalene carboxylic acid amide compound | UENO FINE CHEMICALS INDUSTRY, LTD. (JP) | 2009-05-12 | — | — | US | disclosed |
| US-20080045720-A1 | Method for producing naphthalene carboxylic acid amide compound | UENO FINE CHEMICALS INDUSTRY, LTD. (JP) | 2008-02-21 | — | — | US | disclosed |
| EP-1867629-A2 | Method for producing naphthalene carboxylic acid amide compound | Ueno Fine Chemicals Industry, Ltd. (JP) | 2007-12-19 | — | — | EP | disclosed |
| US-20060231589-A1 | Hydroxynaphthalenedicarboxylic acid hydrazide and derivatives thereof as well as process for preparing them | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO | 2006-10-19 | — | — | US | disclosed |
| EP-1712546-A1 | Hydroxynaphthalenedicarboxylic acid hydrazide and derivatives thereof as well as process for preparing them | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2006-10-18 | — | — | EP | disclosed |
| EP-1283205-B1 | NAPHTHOL DERIVATIVES | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2004-09-22 | — | — | EP | disclosed |
| EP-1283205-A1 | NAPHTHOL DERIVATIVES | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-20020151720-A1 | NAPHTHOL DERIVATIVES | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2002-10-17 | — | — | US | disclosed |
| US-6451988-B1 | AN AZO COMPOUND AND A METAL COMPLEX WHICH ARE SYNTHESIZED WITH THE NAPHTHOL DERIVATIVE | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2002-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151720-A1 | NAPHTHOL DERIVATIVES | NAP1L1, IK, NAP1L4 | ESR1 1221/4885LMNA 640/4885CYP1A2 41/4885 |
| US-20080045720-A1 | Method for producing naphthalene carboxylic acid amide compound | NAAA, AADAC, NAT1 | ESR1 2119/4885LMNA 2657/4885CYP1A2 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.