Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709648 | 1.00 | REN (0.62) | REN | |
| SCHEMBL5709673 | 0.91 | REN (0.54) | REN | |
| SCHEMBL5709572 | 0.88 | REN (0.49) | REN | |
| SCHEMBL5709596 | 0.85 | REN (0.47) | REN | |
| SCHEMBL7348709 | 0.83 | REN (0.78) | REN | |
| SCHEMBL5709608 | 0.82 | REN (0.46) | REN | |
| SCHEMBL9674888 | 0.77 | REN (0.65) | REN | |
| SCHEMBL7411200 | 0.75 | REN (0.66) | REN | |
| SCHEMBL7408319 | 0.75 | REN (0.65) | REN | |
| SCHEMBL7267084 | 0.75 | REN (0.71) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1712227-A1 | Amino diols useful in the treatment of Alzheimer's disease | Elan Pharmaceuticals, Inc. (US) | 2006-10-18 | — | — | EP | claimed |
| US-5314920-A | Renin inhibitors | G. D. SEARLE & CO. (US) | 1994-05-24 | — | — | US | claimed |
| EP-1712227-A1 | Amino diols useful in the treatment of Alzheimer's disease | Elan Pharmaceuticals, Inc. (US) | 2006-10-18 | — | — | EP | disclosed |
| US-5314920-A | Renin inhibitors | G. D. SEARLE & CO. (US) | 1994-05-24 | — | — | US | disclosed |