Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5710175 | 0.80 | TP53 (0.37) | PTGS2GPR84 | |
| SCHEMBL5142259 | 0.79 | TP53 (0.44) | PTGS2CYP3A4 | |
| SCHEMBL10938970 | 0.79 | TP53 (0.44) | PTGS2CYP3A4 | |
| SCHEMBL5175941 | 0.77 | CYP3A4 (0.42) | CYP3A4 | |
| SCHEMBL10945234 | 0.77 | ESR1 (0.42) | PTGS2CYP3A4 | |
| SCHEMBL225100 | 0.76 | PTGS2 (0.48) | PTGS2CYP3A4GPR84 | |
| SCHEMBL31545174 | 0.76 | TYR (0.41) | PTGS2CYP3A4ADRB2 | |
| SCHEMBL20520281 | 0.76 | ESR1 (0.45) | GPR84ADRB2 | |
| SCHEMBL20520248 | 0.76 | ESR1 (0.45) | GPR84ADRB2 | |
| SCHEMBL20520221 | 0.76 | ESR1 (0.45) | GPR84ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179435-B1 | Reversible thermochromic composition having improved light-fastness and product comprising same | PILOT INK CO LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-6946168-B2 | Photochromic phthalein dyes encapsulated in curable oligomers used as coatings on geometric shaped suports as designs | THE PILOT INK CO., LTD. (JP) | 2005-09-20 | — | — | US | disclosed |
| US-20040077743-A1 | Photochromic phthalein dyes encapsulated in curable oligomers used as coatings on geometric shaped suports as designs | THE PILOT INK CO., LTD. | 2004-04-22 | — | — | US | disclosed |
| US-6638620-B2 | Discoloration sensitivity | THE PILOT INK CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| EP-1179435-A1 | Reversible thermochromic composition having improved light-fastness and product comprising same | The Pilot Ink Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |