Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28690072 | 0.98 | NAAA (0.69) | NAAAHTTRAD52NPSR1FAAH | |
| SCHEMBL10353796 | 0.93 | — | — | |
| SCHEMBL50185 | 0.88 | NAAA (0.81) | NAAAHTTRAD52NPSR1FAAH | |
| SCHEMBL3993048 | 0.85 | NAAA (0.86) | NAAAHTTRAD52NPSR1FAAH | |
| SCHEMBL14472850 | 0.85 | NAAA (0.86) | NAAAHTTRAD52NPSR1FAAH | |
| SCHEMBL12956536 | 0.85 | NAAA (0.86) | NAAAHTTRAD52NPSR1FAAH | |
| SCHEMBL2859241 | 0.83 | — | — | |
| SCHEMBL2600809 | 0.83 | NAAA (0.73) | NAAAHTTRAD52NPSR1FAAH | |
| SCHEMBL28397841 | 0.83 | NAAA (0.50) | NAAAHTTRAD52NPSR1FAAH | |
| Ethylene Glycol SCHEMBL50184 | 0.81 | NAAA (0.71) | NAAAHTTRAD52NPSR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102442908-A | Intermediate and method for preparing naproxcinod | TIANJIN INST PHARM RESEARCH | 2012-05-09 | — | — | CN | disclosed |
| EP-1732896-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | Aventis Pharmaceuticals Inc. (US) | 2006-12-20 | — | — | EP | disclosed |
| EP-1295866-B1 | 4-membered ring compound and optical phase retardation plate using the same | FUJI PHOTO FILM CO LTD (JP) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005097750-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMACEUTICALS INC. (US) | 2005-10-20 | — | — | WO | disclosed |
| US-6811833-B2 | BIREFRINGEMENT FILM | FUJI PHOTO FILM CO., LTD. (JP) | 2004-11-02 | — | — | US | disclosed |
| US-20030102458-A1 | 4-Membered ring compound and optical phase optical retardation plate using the same | FUJIFILM CORPORATION (JP) | 2003-06-05 | — | — | US | disclosed |
| EP-1295866-A1 | 4-membered ring compound and optical phase retardation plate using the same | FUJI PHOTO FILM CO., LTD. (JP) | 2003-03-26 | — | — | EP | disclosed |
| US-6114286-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0947516-A1 | N-benzyl substituted, heterocyclic ring-fused pyrimidinone derivatives, their preparation and their use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-10-06 | — | — | EP | disclosed |