Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | RARA | P10276 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MTOR | P42345 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | BID | P55957 | 3/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.55 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.55 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | EP300 | Q09472 | 1/20 | 0.55 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.55 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.55 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.55 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769320 | 1.00 | RARB (0.61) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9715178 | 1.00 | RARB (0.61) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL10596397 | 1.00 | RARB (0.61) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL8769292 | 1.00 | RARB (0.61) | RARBMEN1ALDH1A1RARAMAPT | |
| Terephthalic Acid SCHEMBL9455932 | 0.90 | RARB (0.70) | RARBPPARA | |
| Bicarbonate SCHEMBL27543186 | 0.88 | PPARA (0.57) | PPARABIDMCL1BCL2L1BAK1 | |
| SCHEMBL12505674 | 0.88 | FOLH1 (0.57) | RARBMEN1ALDH1A1RARAMAPT | |
| Bicarbonate SCHEMBL1838555 | 0.88 | PPARA (0.57) | PPARABIDMCL1BCL2L1BAK1 | |
| Bicarbonate SCHEMBL1835039 | 0.88 | PPARA (0.57) | PPARABIDMCL1BCL2L1BAK1 | |
| Bicarbonate SCHEMBL27594350 | 0.88 | PPARA (0.57) | PPARABIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720301-A | Reversible heat sensitive recording composition | PILOT INK CO., LTD. (JP) | 1988-01-19 | — | — | US | claimed |
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | THE PILOT INK CO., LTD. (JP) | 2026-03-05 | — | — | US | disclosed |
| EP-3954745-B1 | REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME | KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) | 2026-01-07 | — | — | EP | disclosed |
| US-12460099-B2 | Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment | THE PILOT INK CO., LTD. (JP) | 2025-11-04 | — | — | US | disclosed |
| US-12421411-B2 | Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument | KABUSHIKI KAISHA PILOT CORPORATION (JP) | 2025-09-23 | — | — | US | disclosed |
| EP-3608386-B1 | REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN | PILOT INK CO LTD (JP) | 2025-02-19 | — | — | EP | disclosed |
| US-12123107-B2 | Reversibly thermochromic composite fiber | KABUSHIKI KAISHA PILOT CORPORATION (JP) | 2024-10-22 | — | — | US | disclosed |
| CN-113646052-B | Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument | 百乐墨水株式会社 | 2024-05-17 | — | — | CN | disclosed |
| EP-3702419-B1 | REVERSIBLE THERMOCHROMIC AQUEOUS INK COMPOSITION AND WRITING INSTRUMENT USING SAME | KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) | 2023-09-20 | — | — | EP | disclosed |
| CN-110446770-B | Reversible thermochromic composition and reversible thermochromic microcapsule pigment containing the same | 百乐墨水株式会社 | 2023-08-08 | — | — | CN | disclosed |
| EP-2772523-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION | Kabushiki Kaisha Pilot Corporation (JP) | 2014-09-03 | — | — | EP | disclosed |
| US-8569208-B1 | Tunable directional color transition compositions and methods of making and using the same | SEGAN INDUSTRIES, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| EP-1179435-B1 | Reversible thermochromic composition having improved light-fastness and product comprising same | PILOT INK CO LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-6638620-B2 | Discoloration sensitivity | THE PILOT INK CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| US-6165234-A | FOR IMPARTING REVERSIBLE COLOR CHANGES TO WAXES AND CANDLES WHEN HEATED OR WHEN WAX MELTS OR WHEN THE CANDLE BURNS | KANAKKANATT SEBASTIAN V (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0617109-B1 | Liquid crystal material, liquid crystal composition and liquid crystal element | MITSUI PETROCHEMICAL IND (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5422039-A | Having a chiral center-containing a tetralinylene ring as well as a second chiral center; cells having high temperature operating range; high switching speed, low voltage and stable contrast | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0617109-A1 | Liquid crystal material, liquid crystal composition and liquid crystal element | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |
| US-4865648-A | ELECTRON DONOR DYE; ESTER; PHENOL, CARBOXY ACID, PHOSPHATE ESTER, TRIAZOLE | KITO TSUTOMU (JP) | 1989-09-12 | — | — | US | disclosed |
| US-4720301-A | Reversible heat sensitive recording composition | PILOT INK CO., LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | TYR, SCO2, HBB | RARB 334/4885MEN1 1317/4885ALDH1A1 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.