SCHEMBL5710451

SCHEMBL5710451

O=C(Oc1ccc(-c2ccccc2)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.67
MAPT P10636 4/20 0.61
TDP1 Q9NUW8 4/20 0.61
KMT2A Q03164 6/20 0.59
MEN1 O00255 3/20 0.59
ALDH1A1 P00352 2/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
PKM P14618 1/20 0.58
PDCD1 Q15116 1/20 0.56
CD274 Q9NZQ7 1/20 0.56
RAB9A P51151 1/20 0.54
PRSS1 P07477 1/20 0.54
ACR P10323 1/20 0.54
TMPRSS15 P98073 1/20 0.54
PDGFRB P09619 1/20 0.54
PDGFRA P16234 1/20 0.54
HSD17B10 Q99714 2/20 0.53
KDM4E B2RXH2 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9189720 1.00 PARP10 (0.67) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL26039015 0.98 PARP10 (0.70) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL26375073 0.98 PARP10 (0.65) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL2638440 0.96 PARP10 (0.67) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL26038599 0.96 PARP10 (0.67) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL2462824 0.96 PARP10 (0.61) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL9189715 0.94 HSD17B10 (0.62) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL13019485 0.94 PARP10 (0.63) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL68278 0.94 PARP10 (0.63) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL6938009 0.94 PARP10 (0.69) PARP10MAPTTDP1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1295866-B1 4-membered ring compound and optical phase retardation plate using the same FUJI PHOTO FILM CO LTD (JP) 2006-11-02 EP disclosed
US-6811833-B2 BIREFRINGEMENT FILM FUJI PHOTO FILM CO., LTD. (JP) 2004-11-02 US disclosed
US-20030102458-A1 4-Membered ring compound and optical phase optical retardation plate using the same FUJIFILM CORPORATION (JP) 2003-06-05 US disclosed
EP-1295866-A1 4-membered ring compound and optical phase retardation plate using the same FUJI PHOTO FILM CO., LTD. (JP) 2003-03-26 EP disclosed