SCHEMBL68278

SCHEMBL68278

O=C(Oc1ccccc1)c1ccc(-c2ccc(C(=O)Oc3ccccc3)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.63
PRSS1 P07477 1/20 0.61
ACR P10323 1/20 0.61
TMPRSS15 P98073 1/20 0.61
MAPT P10636 7/20 0.58
TDP1 Q9NUW8 3/20 0.58
NSD2 O96028 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.57
KMT2A Q03164 5/20 0.56
MEN1 O00255 3/20 0.56
ALDH1A1 P00352 3/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
PKM P14618 1/20 0.55
PDCD1 Q15116 1/20 0.53
CD274 Q9NZQ7 1/20 0.53
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52
HSD17B10 Q99714 1/20 0.52
ALOX5 P09917 1/20 0.51
RAB9A P51151 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13019485 1.00 PARP10 (0.63) PARP10PRSS1ACRTMPRSS15MAPT
SCHEMBL2462824 0.98 PARP10 (0.61) PARP10PRSS1ACRTMPRSS15MAPT
SCHEMBL26375073 0.96 PARP10 (0.65) PARP10PRSS1ACRTMPRSS15MAPT
SCHEMBL3144029 0.94 HSD17B10 (0.59) PARP10PRSS1ACRTMPRSS15MAPT
SCHEMBL5710451 0.94 PARP10 (0.67) PARP10PRSS1ACRTMPRSS15MAPT
SCHEMBL9189720 0.94 PARP10 (0.67) PARP10PRSS1ACRTMPRSS15MAPT
SCHEMBL70034 0.93 PARP10 (0.70) PARP10PRSS1ACRTMPRSS15MAPT
SCHEMBL8334352 0.92 MAPT (0.58) PARP10PRSS1ACRTMPRSS15MAPT
SCHEMBL13019495 0.92 PARP10 (0.61) PARP10PRSS1ACRTMPRSS15MAPT
SCHEMBL13019492 0.92 PARP10 (0.61) PARP10PRSS1ACRTMPRSS15MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4266851-A None JP disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-20100041860-A1 POLYIMIDE, DIAMINE COMPOUND AND METHOD FOR PRODUCING THE SAME UBE INDUSTRIES, LTD. (JP) 2010-02-18 US disclosed
US-20100041860-A1 POLYIMIDE, DIAMINE COMPOUND AND METHOD FOR PRODUCING THE SAME UBE INDUSTRIES, LTD. (JP) 2010-02-18 US disclosed
US-20100041860-A1 POLYIMIDE, DIAMINE COMPOUND AND METHOD FOR PRODUCING THE SAME UBE INDUSTRIES, LTD. (JP) 2010-02-18 US disclosed
EP-1526149-B1 Aromatic amide block copolymer and process of producing the same TOSOH CORP (JP) 2007-05-23 EP disclosed
US-7129314-B2 Aromatic amide block copolymer and process of producing the same TOSOH CORPORATION (JP) 2006-10-31 US disclosed
US-20050090639-A1 Aromatic amide block copolymer and process of producing the same TOSOH CORPORATION (JP) 2005-04-28 US disclosed
EP-1526149-A1 Aromatic amide block copolymer and process of producing the same Tosoh Corporation (JP) 2005-04-27 EP disclosed
US-6110578-A STRUCTURAL UNIT DERIVED FROM HYDROXYCARBOXYLIC ACID, A STRUCTURAL UNIT DERIVED FROM MOLECULAR WEIGHT INCREASING AGENT AND/OR A STRUCTURAL UNIT DERIVED FROM POLYMERIZATION CATALYST DEACTIVATOR. DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-08-29 US disclosed
US-6037384-A POLYLACTONE AND POLYMERIZATION CATALYST DEACTIVATOR; BIODEGRADABLE, STORAGE STABILITY, HEAT RESISTANCE, IMPACT STRENGTH, MOLDABILITY; PACKAGING, INSULATION, CUSHIONS DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-03-14 US disclosed
US-5439976-A Block addtion polymers with terminal hydroxy groups blended with polyesters KURARAY COMPANY LTD. (JP) 1995-08-08 US disclosed
EP-0607961-A2 Polyester composition and process for producing the same KURARAY CO., LTD. (JP) 1994-07-27 EP disclosed
JP-H04266851-A PURIFICATION OF AROMATIC DICARBOXYLIC ACID DIPHENYL ESTER MITSUI PETROCHEM IND LTD 1992-09-22 JP disclosed
US-4983707-A Heat resistance; melt processability MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1991-01-08 US disclosed
EP-0382438-A2 Copolyester MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1990-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 PARP10 1526/4885PRSS1 3344/4885ACR 487/4885
US-20100041860-A1 POLYIMIDE, DIAMINE COMPOUND AND METHOD FOR PRODUCING THE SAME DDC, AOC1, DDT PARP10 347/4885PRSS1 4140/4885ACR 649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.