SCHEMBL5710458

SCHEMBL5710458

O=C(O)c1ccc(-c2ccccc2)cc1.Oc1ccc(-c2ccccc2)cc1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.74
CA12 O43570 1/20 0.73
CA1 P00915 1/20 0.73
CA2 P00918 1/20 0.73
CA3 P07451 1/20 0.73
TYR P14679 1/20 0.73
DRD1 P21728 1/20 0.73
CA4 P22748 1/20 0.73
CA6 P23280 1/20 0.73
CA5A P35218 1/20 0.73
CA7 P43166 1/20 0.73
CA9 Q16790 1/20 0.73
CA14 Q9ULX7 1/20 0.73
CA5B Q9Y2D0 1/20 0.73
RAB9A P51151 3/20 0.69
MAPT P10636 2/20 0.69
MEN1 O00255 1/20 0.69
LMNA P02545 1/20 0.69
KMT2A Q03164 1/20 0.69
BCL2L1 Q07817 2/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Paraben SCHEMBL8089146 1.00 EGFR (0.74) EGFRCA12CA1CA2CA3
Terephthalic Acid SCHEMBL9189723 1.00 EGFR (0.74) EGFRCA12CA1CA2CA3
Terephthalic Acid SCHEMBL10442831 1.00 EGFR (0.74) EGFRCA12CA1CA2CA3
Biphenyl SCHEMBL9152460 0.98 CA12 (0.76) EGFRCA12CA1CA2CA3
Biphenyl SCHEMBL21143372 0.98 CA12 (0.76) EGFRCA12CA1CA2CA3
Benzoic Acid SCHEMBL1902601 0.95 RAB9A (0.69) EGFRCA12CA1CA2CA3
Benzoic Acid SCHEMBL27545230 0.93 RAB9A (0.67) EGFRCA12CA1CA2CA3
Benzoic Acid SCHEMBL9011861 0.93 RAB9A (0.72) EGFRCA12CA1CA2CA3
Phenol SCHEMBL9013973 0.93 EGFR (0.70) EGFRCA12CA1CA2CA3
Terephthalic Acid SCHEMBL9715863 0.93 CA12 (0.84) EGFRCA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1295866-B1 4-membered ring compound and optical phase retardation plate using the same FUJI PHOTO FILM CO LTD (JP) 2006-11-02 EP disclosed
US-6811833-B2 BIREFRINGEMENT FILM FUJI PHOTO FILM CO., LTD. (JP) 2004-11-02 US disclosed
US-20030102458-A1 4-Membered ring compound and optical phase optical retardation plate using the same FUJIFILM CORPORATION (JP) 2003-06-05 US disclosed
EP-1295866-A1 4-membered ring compound and optical phase retardation plate using the same FUJI PHOTO FILM CO., LTD. (JP) 2003-03-26 EP disclosed