SCHEMBL57106

SCHEMBL57106

CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 13/20 0.53
HPGD P15428 1/20 0.51
RECQL P46063 1/20 0.49
EPHX1 P07099 1/20 0.49
USP2 O75604 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29981135 0.94 HPGD (0.54) GPR119HPGDRECQLEPHX1USP2
SCHEMBL31496241 0.94 GPR119 (0.61) GPR119HPGDRECQLEPHX1USP2
SCHEMBL4008565 0.94 HPGD (0.54) GPR119HPGDRECQLEPHX1USP2
SCHEMBL13060395 0.92 HPGD (0.66) GPR119HPGDRECQL
SCHEMBL31565588 0.91 GPR119 (0.55) GPR119HPGD
SCHEMBL330785 0.91 GPR119 (0.48) GPR119HPGDRECQLEPHX1USP2
SCHEMBL66134 0.91 GPR119 (0.48) GPR119HPGDRECQLEPHX1USP2
SCHEMBL66145 0.91 GPR119 (0.48) GPR119HPGDRECQLEPHX1USP2
SCHEMBL21178227 0.88 GPR119 (0.47) GPR119HPGD
SCHEMBL21192130 0.88 GPR119 (0.47) GPR119HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2336 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552790-B2 Positive modulators of the muscarinic acetylcholine receptor M4 VANDERBILT UNIVERSITY (US) 2026-02-17 US claimed
US-20250136600-A1 POSITIVE MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 VANDERBILT UNIVERSITY 2025-05-01 US claimed
CN-111171023-B Compound with Pim1 inhibitory activity and preparation method and medical application thereof 中国药科大学 2021-12-21 CN claimed
CN-112225722-A Method for preparing crizotinib intermediate by using microchannel reactor 张家港威胜生物医药有限公司 2021-01-15 CN claimed
CN-111171023-A Compound with Pim1 inhibitory activity and preparation method and medical application thereof 中国药科大学 2020-05-19 CN claimed
US-20260146050-A1 KRAS DEGRADING COMPOUNDS COMPRISING SPIROCYCLIC ANNULATED 2 AMINO-3-CYANO THIOPHENES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2026-05-28 US disclosed
EP-4747250-A1 KINASE INHIBITORS The United States Of America, As Represented By The Secretary, Department of Health and Human Services (US) 2026-05-27 EP disclosed
US-12637451-B2 Amino quinazoline derivatives as P2X3 inhibitors CHIESI FARMACEUTICI S.P.A. (IT) 2026-05-26 US disclosed
CN-115943145-B Pyrazolopyrimidine compounds as ATR kinase inhibitors BEIJING TIDE PHARMACEUTICAL CO.,LTD. (CN) 2026-05-26 CN disclosed
EP-4743453-A1 MODULATORS OF MITOCHONDRIAL DNA REPLICATION Pretzel Therapeutics, Inc. (US) 2026-05-20 EP disclosed
EP-3364967-B1 FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2026-05-20 EP disclosed
US-12629367-B2 Five-membered ring-fused six-membered ring compound, preparation method therefor, and pharmaceutical composition and use thereof HANGZHOU POLYMED BIOPHARMACEUTICALS, INC. (CN) 2026-05-19 US disclosed
EP-0612729-A2 Pyridine derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1994-08-31 EP disclosed
CN-1077716-A ANTIVIRAL PEPTIDES PFIZER (US) 1993-10-27 CN disclosed
US-5246948-A Antiinflammatory, antipyretic, analgesic, antiallergic, immunosupressing or immunomodulating activity TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-09-21 US disclosed
WO-1993018003-A1 SUBSTITUED PIPECOLINIC ACID DERIVATIVES AS HIV PROTEASE INHIBITORS BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1993-09-16 WO disclosed
EP-0560268-A1 Substituted pipecolinic acid derivatives as HIV protease inhibitors BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1993-09-15 EP disclosed
EP-0522606-A2 Pyridine derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-01-13 EP disclosed
EP-0500835-A1 A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE. DAE WOONG PHARMA (KR) 1992-09-02 EP disclosed
WO-1992004342-A1 A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 1992-03-19 WO disclosed