Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LSS | P48449 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5649311 | 0.92 | LSS (0.54) | MEN1KMT2ALSSSIGMAR1CHRNA7 | |
| Hydrochloric Acid SCHEMBL9469824 | 0.91 | LSS (0.53) | MEN1KMT2ALSSSIGMAR1CHRNA7 | |
| SCHEMBL1542730 | 0.88 | LSS (0.51) | MEN1KMT2ALSSSIGMAR1CHRNA7 | |
| SCHEMBL5419769 | 0.88 | LSS (0.51) | MEN1KMT2ALSSSIGMAR1CHRNA7 | |
| SCHEMBL1542442 | 0.88 | LSS (0.51) | MEN1KMT2ALSSSIGMAR1CHRNA7 | |
| SCHEMBL5710504 | 0.80 | LSS (0.53) | LSSCHRNA7 | |
| SCHEMBL5710328 | 0.80 | LSS (0.53) | LSSCHRNA7 | |
| SCHEMBL5706609 | 0.80 | LSS (0.53) | LSSCHRNA7 | |
| SCHEMBL5710323 | 0.80 | LSS (0.53) | LSSCHRNA7 | |
| SCHEMBL9469598 | 0.80 | MEN1 (0.63) | MEN1KMT2ALSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735305-A2 | 3-QUINUCLIDINYL HETEROATOM BRIDGED BIARYL DERIVATIVES | ABBOTT LABORATORIES (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005066167-A2 | 3-QUINUCLIDINYL HETEROATOM BRIDGED BIARYL DERIVATIVES | ABBOTT LABORATORIES (US) | 2005-07-21 | — | — | WO | disclosed |