Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 17/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5710579 | 0.99 | P2RX7 (0.49) | P2RX7EPHX2MEN1ALDH1A1HPGD | |
| SCHEMBL5710719 | 0.86 | P2RX7 (0.54) | P2RX7MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL5710446 | 0.86 | P2RX7 (0.42) | P2RX7EPHX2MEN1ALDH1A1KMT2A | |
| SCHEMBL5710464 | 0.85 | P2RX7 (0.53) | P2RX7MEN1ALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL5710441 | 0.85 | P2RX7 (0.53) | P2RX7MEN1ALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL6687069 | 0.78 | CDK1 (0.36) | ALDH1A1HPGD | |
| SCHEMBL5710569 | 0.77 | P2RX7 (0.65) | P2RX7MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL5773216 | 0.76 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL7568729 | 0.71 | P2RX7 (0.54) | P2RX7MEN1ALDH1A1KMT2A | |
| SCHEMBL5773010 | 0.69 | P2RX7 (0.63) | P2RX7MEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448195-B1 | N-ADAMANTYLMETHYL DERIVATES AND INTERMEDIATES AS PHARMACEUTICAL COMPOSITIONS AND PROCESSES FOR THEIR PREPARATION | ASTRAZENECA AB (SE) | 2006-11-02 | — | — | EP | claimed |