Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | ECE1 | P42892 | 2/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19607509 | 0.91 | CTSL (0.55) | ATMCTSLCTSSCTSKECE1 | |
| SCHEMBL9829374 | 0.90 | ATM (0.63) | ATMALDH1A1CTSDADAMTS4CTSL | |
| SCHEMBL9829383 | 0.90 | ATM (0.63) | ATMALDH1A1CTSDADAMTS4CTSL | |
| SCHEMBL7870090 | 0.88 | ATM (0.60) | ATMALDH1A1CTSDCTSLCTSS | |
| SCHEMBL7870088 | 0.88 | ATM (0.60) | ATMALDH1A1CTSDCTSLCTSS | |
| SCHEMBL11816446 | 0.86 | ATM (0.67) | ATMALDH1A1CTSLCTSSCTSK | |
| SCHEMBL8604954 | 0.86 | CTSL (0.51) | ATMCTSLCTSSCTSKECE1 | |
| SCHEMBL10441764 | 0.86 | ATM (0.67) | ATMALDH1A1CTSLCTSSCTSK | |
| SCHEMBL6149680 | 0.86 | CTSL (0.51) | ATMCTSLCTSSCTSKECE1 | |
| SCHEMBL220569 | 0.85 | CTSL (0.63) | ATMCTSLCTSSCTSKECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-1103560-A1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-05-30 | — | — | EP | disclosed |