Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 8/20 | 0.71 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3144779 | 0.95 | PREP (0.66) | PREPACENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10370731 | 0.95 | PREP (0.66) | PREPACENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5711239 | 0.89 | PREP (0.72) | PREPKMT2ANPSR1 | |
| SCHEMBL10516263 | 0.88 | PREP (0.72) | PREPNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL10516273 | 0.88 | PREP (0.72) | PREPNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL8077466 | 0.86 | PREP (0.62) | PREPNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8077468 | 0.86 | PREP (0.62) | PREPNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10516460 | 0.84 | PREP (0.64) | PREP | |
| SCHEMBL10518225 | 0.84 | PREP (0.64) | PREPNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10518215 | 0.84 | PREP (0.64) | PREPNPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |