Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 11/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077466 | 1.00 | PREP (0.62) | PREPNPC1RAB9ASMN1; SMN2DPP4 | |
| SCHEMBL10518215 | 0.94 | PREP (0.64) | PREPNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10518225 | 0.94 | PREP (0.64) | PREPNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10516460 | 0.87 | PREP (0.64) | PREP | |
| SCHEMBL10516451 | 0.87 | PREP (0.64) | PREP | |
| SCHEMBL10518549 | 0.86 | PREP (0.62) | PREPNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10518539 | 0.86 | PREP (0.62) | PREPNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5711258 | 0.86 | PREP (0.71) | PREPNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10370731 | 0.85 | PREP (0.66) | PREPNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3144779 | 0.85 | PREP (0.66) | PREPNPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4857524-A | Thiazolidine compounds and therapeutic method | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| JP-1042475-A | — | — | None | — | — | JP | disclosed |
| US-6121311-A | Method for treating cocainism | JAPAN TOBACCO INC. (JP) | 2000-09-19 | — | — | US | disclosed |
| US-4857524-A | Thiazolidine compounds and therapeutic method | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| US-4857524-A | Thiazolidine compounds and therapeutic method | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0303434-A1 | Thiazolidine compounds | Kissei Pharmaceutical Co. Ltd. (JP) | 1989-02-15 | — | — | EP | disclosed |