Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 5/20 | 0.43 |
| ▸ | CMA1 | P23946 | 4/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | F11 | P03951 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711368 | 0.90 | CMA1 (0.51) | F2CMA1MMP2MMP3MMP7 | |
| SCHEMBL5711332 | 0.87 | CAPN1 (0.46) | CAPN1CYP3A4CMA1MMP2MMP3 | |
| SCHEMBL5711190 | 0.85 | CAPN1 (0.45) | CAPN1CYP3A4F2CMA1CTSL | |
| SCHEMBL5711319 | 0.85 | CAPN1 (0.50) | CAPN1CYP3A4CMA1CTSLCTSB | |
| SCHEMBL7666940 | 0.85 | CAPN1 (0.50) | CAPN1CYP3A4CMA1CTSLCTSB | |
| SCHEMBL7665212 | 0.85 | F2 (0.42) | CAPN1CYP3A4F2CMA1F10 | |
| SCHEMBL7663175 | 0.84 | CYP3A4 (0.45) | CAPN1CYP3A4CMA1CTSLCTSB | |
| SCHEMBL5711290 | 0.83 | PRSS8 (0.49) | CAPN1CYP3A4 | |
| SCHEMBL7662793 | 0.83 | CMA1 (0.56) | CAPN1CMA1 | |
| SCHEMBL7662788 | 0.83 | CMA1 (0.56) | CAPN1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-1103560-A1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-05-30 | — | — | EP | disclosed |