Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | AADAC | P22760 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | LCAT | P04180 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57855 | 0.87 | KCNH2 (0.53) | KCNH2EPHX2FAAHAADACPTGS1 | |
| SCHEMBL13281330 | 0.87 | KCNH2 (0.53) | KCNH2EPHX2FAAHAADACPTGS1 | |
| SCHEMBL3036120 | 0.85 | KCNH2 (0.52) | KCNH2EPHX2FAAHAADACPTGS1 | |
| SCHEMBL15441879 | 0.83 | KCNH2 (0.50) | KCNH2EPHX2FAAHAADACPTGS1 | |
| SCHEMBL13278969 | 0.78 | KCNH2 (0.53) | KCNH2EPHX2FAAHAADACPTGS1 | |
| SCHEMBL14405200 | 0.77 | KCNH2 (0.46) | KCNH2EPHX2FAAHAADACPTGS1 | |
| SCHEMBL2095407 | 0.77 | KCNH2 (0.46) | KCNH2EPHX2FAAHAADACPTGS1 | |
| SCHEMBL3664766 | 0.75 | KCNH2 (0.67) | KCNH2EPHX2FAAHAADACPTGS1 | |
| SCHEMBL3664769 | 0.75 | KCNH2 (0.67) | KCNH2EPHX2FAAHAADACPTGS1 | |
| SCHEMBL2056202 | 0.75 | KCNH2 (0.58) | KCNH2EPHX2FAAHPTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727782-A1 | METHOD OF PRODUCING AMINOPHENOL COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005092832-A1 | METHOD OF PRODUCING AMINOPHENOL COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-10-06 | — | — | WO | disclosed |