Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.48 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27583508 | 0.90 | SMN1; SMN2 (0.50) | GRM2GRM3SMN1; SMN2HIF1ALMNA | |
| SCHEMBL1167642 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2HIF1ALMNAALDH1A1MAPK1 | |
| SCHEMBL1167641 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2HIF1ALMNAALDH1A1MAPK1 | |
| SCHEMBL10855143 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1ALMNAALDH1A1MAPK1 | |
| SCHEMBL27484782 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1ALMNAALDH1A1MAPK1 | |
| SCHEMBL10855149 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1ALMNAALDH1A1MAPK1 | |
| SCHEMBL5033585 | 0.86 | ALDH1A1 (0.46) | SMN1; SMN2HIF1ALMNAALDH1A1MAPK1 | |
| SCHEMBL2963546 | 0.86 | CETP (0.48) | SMN1; SMN2HIF1AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8674203 | 0.86 | CETP (0.48) | SMN1; SMN2HIF1AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL149592 | 0.86 | ALDH1A1 (0.49) | SMN1; SMN2HIF1ALMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |