Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11639333 | 0.95 | CYP2D6 (0.39) | LMNAHTTSMN1; SMN2KDM4EALOX12 | |
| SCHEMBL8778184 | 0.87 | KCNA5 (0.36) | LMNAHTTSMN1; SMN2KDM4EALOX12 | |
| SCHEMBL4685253 | 0.83 | HDAC8 (0.32) | LMNAKDM4ECYP1A2 | |
| SCHEMBL8629466 | 0.83 | SMN1; SMN2 (0.31) | LMNASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL10972097 | 0.82 | TDP1 (0.34) | LMNAKDM4ENPC1RAB9ACYP1A2 | |
| SCHEMBL4697503 | 0.81 | HDAC8 (0.31) | — | |
| SCHEMBL4686082 | 0.81 | HDAC8 (0.31) | — | |
| SCHEMBL4697504 | 0.81 | FLT3 (0.32) | LMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL4686084 | 0.81 | FLT3 (0.32) | LMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL4681960 | 0.81 | HDAC8 (0.33) | LMNASMN1; SMN2KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591228-B | Chiral styryl pyridyl sulfoxide and synthesis method thereof | 浙江大学杭州国际科创中心 | 2024-06-14 | — | — | CN | claimed |
| CN-114591228-B | Chiral styryl pyridyl sulfoxide and synthesis method thereof | 浙江大学杭州国际科创中心 | 2024-06-14 | — | — | CN | disclosed |
| CN-114591228-B | Chiral styryl pyridyl sulfoxide and synthesis method thereof | 浙江大学杭州国际科创中心 | 2024-06-14 | — | — | CN | disclosed |
| CN-114591228-A | Chiral styryl pyridyl sulfoxide and synthesis method thereof | 浙江大学杭州国际科创中心 | 2022-06-07 | — | — | CN | disclosed |
| CN-114591228-A | Chiral styryl pyridyl sulfoxide and synthesis method thereof | 浙江大学杭州国际科创中心 | 2022-06-07 | — | — | CN | disclosed |
| CN-104177390-A | Preparation method for pyridyl boric acid | UNIV CHINA PHARMA | 2014-12-03 | — | — | CN | disclosed |
| EP-1288217-B1 | Preparation of dialkylpyridylboranes | PFIZER PROD INC (US) | 2006-03-29 | — | — | EP | disclosed |
| US-6570017-B2 | Reacting a Grigand reagent with borane compound | PFIZER INC | 2003-05-27 | — | — | US | disclosed |
| US-20030083312-A1 | PREPARATION OF DIALKYLPYRIDYLBORANES | PFIZER INC. | 2003-05-01 | — | — | US | disclosed |
| CN-1401649-A | Process for preparing dialkylpyridyl borane | PFIZER PROD INC (US) | 2003-03-12 | — | — | CN | disclosed |
| EP-1288217-A2 | Preparation of dialkylpyridylboranes | Pfizer Products Inc. (US) | 2003-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083312-A1 | PREPARATION OF DIALKYLPYRIDYLBORANES | BMX, RDX, BRIX1 | LMNA 1591/4885HTT 2335/4885SMN1; SMN2 4282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.