BRIX1

Ribosome biogenesis protein BRX1 homolog · Q8TDN6 · BRIX1 on Sugi Atlas →

0 patent compounds predicted against BRIX1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to BRIX1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure PHASE2COMPLETED
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
Phase 1/ Phase 2 Study to Assess Safety and Efficacy of Orally Administered JBI-802 in Subjects With Myeloproliferative Neoplasms (MPN) and Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) With Thrombocytosis PHASE1/PHASE2RECRUITING
A Study Evaluating Megestrol Acetate Modulation in Hormone Receptor Positive Advanced Breast Cancer PHASE2UNKNOWN
Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer PHASE1/PHASE2SUSPENDED
Breakpoint Analysis of de Novo Apparently Balanced Chromosomal Translocations EARLY_PHASE1COMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
A Study of the Genetic Analysis of Brain Disorders nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma nanCOMPLETED
Mapping Disease Pathways for Biliary Atresia nanRECRUITING
Expression Pattern of HNRNPH1 and HNRNPK Genes in MPNs nanUNKNOWN
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives nanUNKNOWN
Molecular Profile of the Evolution of Inclusion Body Myositis nanCOMPLETED
Thermogenic Silencer Regulatory Factors in Humans nanACTIVE_NOT_RECRUITING
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Target of Suv420h1/2 in Hepatocytes nanRECRUITING
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus nanACTIVE_NOT_RECRUITING
Mutations and Phenotypes of Unclassifiable Inherited Bone Marrow Failure Syndromes nanRECRUITING
Impact of Bariatric and Metabolic Surgery on the Reduction of Premature Aging. nanCOMPLETED
Microarray Analysis in Syndromic Obesity nanCOMPLETED
X-chromosome Inactivation, Epigenetics and the Transcriptome nanCOMPLETED
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a BRIX1 binder may also engage these)

ProteinNameSimilarity
Q9DCA5 1.000 Q9DCA5 →
Q3SZZ0 1.000 Q3SZZ0 →
Q5RAN2 1.000 Q5RAN2 →
Q4QQT6 0.999 Q4QQT6 →
Q8UVY2 0.998 Q8UVY2 →
Q9VZE6 0.986 Q9VZE6 →
Q9ASU7 0.976 Q9ASU7 →
Q9HGL6 0.976 Q9HGL6 →
Q7TND5 0.972 Q7TND5 →
Q8K339 0.972 Q8K339 →
P34524 0.971 P34524 →
Q5PQR5 0.971 Q5PQR5 →
Q5RJS9 0.970 Q5RJS9 →
Q6GNS3 0.970 Q6GNS3 →
Q5R631 0.970 Q5R631 →
Q74ZK6 0.970 Q74ZK6 →
NAT10 RNA cytidine acetyltransferase 0.970 landscape →
Q9V411 0.969 Q9V411 →
Q9AWM9 0.969 Q9AWM9 →
Q9H9Y2 0.969 Q9H9Y2 →
Q69ZX6 0.969 Q69ZX6 →
O44411 0.969 O44411 →
Q99P77 0.969 Q99P77 →
Q99LH1 0.968 Q99LH1 →
Q8AVP1 0.968 Q8AVP1 →
B4LNA1 0.968 B4LNA1 →
GTPBP4 GTP-binding protein 4 0.968 landscape →
Q99ME9 0.968 Q99ME9 →
Q8VHZ7 0.968 Q8VHZ7 →
Q9VUV9 0.968 Q9VUV9 →