Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69321 | 0.83 | ALDH1A1 (0.62) | FFAR1KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL29409566 | 0.83 | ALDH1A1 (0.62) | FFAR1KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL30022461 | 0.81 | CA1 (0.60) | HTTFFAR1KMT2APTGDR2KDM4E | |
| SCHEMBL4214499 | 0.81 | CA1 (0.60) | HTTFFAR1KMT2APTGDR2KDM4E | |
| SCHEMBL29365231 | 0.79 | HTT (0.78) | HTTKMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL3527 | 0.79 | HTT (0.78) | HTTKMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL28354531 | 0.79 | SLC16A3 (0.54) | FFAR1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL6511422 | 0.79 | FFAR1 (0.64) | FFAR1KMT2APTGDR2CA12CA1 | |
| SCHEMBL670658 | 0.79 | FFAR1 (0.52) | HTTFFAR1KMT2APTGDR2ALDH1A1 | |
| Fluoride SCHEMBL3190250 | 0.77 | HTT (0.75) | HTTKMT2AKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720825-A1 | NEW COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | Active Biotech AB (SE) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005075410-A1 | NEW COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | ACTIVE BIOTECH AB (SE) | 2005-08-18 | — | — | WO | disclosed |