Ursolic Acid

Ursolic Acid

SCHEMBL5713287

C[C@H]1[C@H](C)CC[C@]2(C(=O)O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@H]12.C[C@H]1[C@H](C)CC[C@]2(C(=O)O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 6/20 1.00
SENP1 Q9P0U3 4/20 1.00
POLB P06746 3/20 1.00
HSD11B1 P28845 3/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
PTPN2 P17706 2/20 1.00
PTPN6 P29350 2/20 1.00
GPBAR1 Q8TDU6 2/20 1.00
USP7 Q93009 2/20 1.00
RECQL P46063 2/20 1.00
AKR1B10 O60218 1/20 1.00
CTSD P07339 1/20 1.00
PTPRF P10586 1/20 1.00
CYP19A1 P11511 1/20 1.00
CETP P11597 1/20 1.00
AKR1B1 P15121 1/20 1.00
CES1 P23141 1/20 1.00
ACP1 P24666 1/20 1.00
EPHX2 P34913 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ursolic Acid SCHEMBL18428537 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL18821200 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL14132123 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL13395361 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL19714770 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL23314191 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL16994210 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL12300180 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL21819718 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL18806320 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8741323-B2 External skin agent comprising modified clay for preventing inflammation POLA CHEMICAL INDUSTRIES INC. (JP) 2014-06-03 US claimed
CN-109438547-A One kind having active ursolic acid derivative of anti-clear cell carcinoma of kidney and the preparation method and application thereof 山东中医药大学 2019-03-08 CN disclosed
CN-107325150-A A kind of method of supercritical carbon dioxide extracting fruit of glossy privet ursolic acid 广东药科大学 2017-11-07 CN disclosed
CN-102421445-A Method for producing nutraceutical composition and nutraceutical produced by the method SAN LIANG WOON 2012-04-18 CN disclosed
CN-102286059-A Method for extracting ursolic acid, carnosic acid and rosmarinic acid from rosmarinus officinalis 2011-12-21 CN disclosed
EP-1732500-A2 COSMETIC COMPOSITION AND METHOD FOR RETARDING HAIR GROWTH E-L Management Corp. (US) 2006-12-20 EP disclosed
WO-2005067627-A2 COSMETIC COMPOSITION AND METHOD FOR RETARDING HAIR GROWTH E-L MANAGEMENT CORPORATION (US) 2005-07-28 WO disclosed