Ursolic Acid

Ursolic Acid

SCHEMBL19714770

C[C@H]1[C@H](C)CC[C@]2(C(=O)O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 6/20 1.00
SENP1 Q9P0U3 4/20 1.00
POLB P06746 3/20 1.00
HSD11B1 P28845 3/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
PTPN2 P17706 2/20 1.00
PTPN6 P29350 2/20 1.00
GPBAR1 Q8TDU6 2/20 1.00
USP7 Q93009 2/20 1.00
RECQL P46063 2/20 1.00
AKR1B10 O60218 1/20 1.00
CTSD P07339 1/20 1.00
PTPRF P10586 1/20 1.00
CYP19A1 P11511 1/20 1.00
CETP P11597 1/20 1.00
AKR1B1 P15121 1/20 1.00
CES1 P23141 1/20 1.00
ACP1 P24666 1/20 1.00
EPHX2 P34913 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ursolic Acid SCHEMBL18428537 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL18821200 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL14132123 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL13395361 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL5713287 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL23314191 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL16994210 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL12300180 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL21819718 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1
Ursolic Acid SCHEMBL18806320 1.00 PTPN1 (1.00) PTPN1SENP1POLBHSD11B1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170360673-A1 HAIR COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2017-12-21 US claimed
US-12507703-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-12-30 US disclosed
US-20250169516-A1 METHODS, DEVICES AND COMPOSITIONS FOR PRESERVING HUMAN MILK THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-05-29 US disclosed
US-12239142-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-03-04 US disclosed
US-20240268402-A1 Methods, Devices and Compositions for Preserving Human Milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2024-08-15 US disclosed
CN-118079876-A Application of ursolic acid as affinity resin ligand and separation and purification of phycocyanin 中国水产科学研究院黄海水产研究所 2024-05-28 CN disclosed
CN-106691902-B Compositions comprising extracts of Ampelopsis grossedentata and Albizzia julibrissin and methods of use 强生消费者公司 2021-04-20 CN disclosed
US-10456344-B2 Hair composition CONOPCO, INC. (US) 2019-10-29 US disclosed
WO-2019164836-A1 SYSTEMS AND METHODS FOR COMBINED COSMETIC TREATMENT OF CELLULITE WITH ULTRASOUND ULTHERA, INC. (US) 2019-08-29 WO disclosed
US-20170360673-A1 HAIR COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2017-12-21 US disclosed
CN-101891794-B Ursolic acid piperazine derivative having antitumor activity and preparation method thereof UNIV FUZHOU 2012-04-25 CN disclosed
CN-102351939-A Method for preparing high-purity ursolic acid and oleanolic acid from ligustrum lucidum ait CHAO ZENG 2012-02-15 CN disclosed
CN-102329362-A Ursolic acid derivative chemically modified by polyethylene glycol and preparation method of ursolic acid derivative UNIV FUZHOU 2012-01-25 CN disclosed
CN-101792477-B Acetyl ursolic acid acylate triethanolamine monoester with anti-cancer activity and preparation method thereof UNIV FUZHOU 2011-10-12 CN disclosed
CN-101928321-A Acidic amino acid chemically-modified ursolic acid derivatives with anti-cancer activities UNIV FUZHOU 2010-12-29 CN disclosed
CN-101928322-A Ursolic acid modifier polyol monoesters with anti-cancer activity UNIV FUZHOU 2010-12-29 CN disclosed
CN-101891794-A Ursolic acid piperazine derivative having antitumor activity and preparation method thereof UNIV FUZHOU 2010-11-24 CN disclosed
CN-101891793-A Method for preparing high-purity ursolic acid from salvia CHAO ZENG 2010-11-24 CN disclosed
CN-101891795-A Ursolic acid diethanol amine derivative with anti-tumor activity and preparation method thereof UNIV FUZHOU 2010-11-24 CN disclosed
CN-101422465-A Use of ursolic acid and plant extract containing the same SHANGHAI WENDA BIOTECH INC (CN) 2009-05-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12507703-B2 Methods, devices and compositions for preserving human milk LPL, CEL, LPO PTPN1 4634/4885SENP1 130/4885POLB 1376/4885
US-10456344-B2 Hair composition GLS2, GLS, LHCGR PTPN1 4867/4885SENP1 4498/4885POLB 2165/4885
US-20170360673-A1 HAIR COMPOSITION GLS2, GLS, CYP17A1 PTPN1 4870/4885SENP1 4505/4885POLB 2197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.