SCHEMBL5713301

SCHEMBL5713301

CCCCc1c(N)cc(C)c(Nc2ccccc2)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.43
RAPGEF4 Q8WZA2 3/20 0.38
MAPT P10636 3/20 0.38
LMNA P02545 2/20 0.38
HSD17B10 Q99714 2/20 0.38
XBP1 P17861 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TLR7 Q9NYK1 1/20 0.37
KCNH3 Q9ULD8 1/20 0.35
IDO1 P14902 2/20 0.35
TLR8 Q9NR97 4/20 0.35
PDE4A P27815 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34
PDE3B Q13370 1/20 0.34
PDE3A Q14432 1/20 0.34
CYP1A2 P05177 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7706521 0.89 SKP2 (0.43) SKP2RAPGEF4MAPTLMNAHSD17B10
SCHEMBL15854826 0.79 RAPGEF4 (0.53) SKP2RAPGEF4MAPTLMNAHSD17B10
SCHEMBL28313595 0.77 MAPT (0.43) SKP2MAPTLMNAHSD17B10XBP1
SCHEMBL21629706 0.75 HSD17B10 (0.43) MAPTLMNAHSD17B10XBP1HTT
SCHEMBL8026165 0.74 MAPT (0.40) SKP2MAPTLMNAHSD17B10XBP1
SCHEMBL27512209 0.74 MAPT (0.43) SKP2MAPTLMNAHSD17B10XBP1
SCHEMBL16682976 0.73 RAPGEF4 (0.50) RAPGEF4MAPTLMNAHSD17B10XBP1
SCHEMBL28232186 0.72 MAPT (0.44) MAPTLMNAHSD17B10XBP1HTT
SCHEMBL7098349 0.72 MAPT (0.44) SKP2MAPTLMNAHSD17B10XBP1
SCHEMBL18733794 0.72 RAPGEF4 (0.46) RAPGEF4MAPTLMNAHSD17B10HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024145438-A1 CURED EPOXY RESIN AND METHOD OF CURING AN EPOXY RESIN USING AN AMINE COMPOUND SI GROUP, INC. (US) 2024-07-04 WO disclosed
CN-118032800-A Terahertz Characterization of Multi-Layer Tire Tread 固特异轮胎和橡胶公司 2024-05-14 CN disclosed
US-20240102926-A1 TERAHERTZ CHARACTERIZATION OF A MULTI-LAYERED TIRE TREAD THE GOODYEAR TIRE & RUBBER COMPANY 2024-03-28 US disclosed
EP-4331821-A1 METHOD AND APPARATUS FOR TERAHERTZ CHARACTERIZATION OF A MULTI-LAYERED TIRE TREAD The Goodyear Tire & Rubber Company (US) 2024-03-06 EP disclosed
US-11874223-B1 Terahertz characterization of a multi-layered tire tread THE GOODYEAR TIRE & RUBBER COMPANY (US) 2024-01-16 US disclosed
WO-2012050657-A1 HYDROCARBON POLYMER MODIFIERS FOR ELASTOMERIC COMPOSITIONS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-04-19 WO disclosed
EP-1057663-B1 Pneumatic run flat tire HANKOOK TIRE CO LTD (KR) 2006-06-07 EP disclosed
US-6422279-B1 Pneumatic run flat tire HANKOOK TIRE MFG. CO., LTD (KR) 2002-07-23 US disclosed
US-6274662-B1 OVERCOATING BARIUM SULFATE WITH POLYSILOXANE J.M. HUBER CORPORATION 2001-08-14 US disclosed
US-6182728-B1 Pneumatic run flat tire HANKOOK TIRE 2001-02-06 US disclosed
EP-0649446-B1 METHOD AND COMPOSITION FOR USING SUBSTITUTED MELAMINES AS NOVOLAK RESIN CURING AGENTS MICHELIN & CIE (FR) 1999-12-15 EP disclosed
EP-0649446-A1 METHOD AND COMPOSITION FOR USING SUBSTITUTED MELAMINES AS NOVOLAK RESIN CURING AGENTS COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN-MICHELIN & CIE (FR) 1995-04-26 EP disclosed
WO-1994001493-A1 METHOD AND COMPOSITION FOR USING SUBSTITUTED MELAMINES AS NOVOLAK RESIN CURING AGENTS COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN - MICHELIN & CIE (FR) 1994-01-20 WO disclosed
US-4525430-A HIGH ELECTRICAL RESISTANCE N.V. BEKAERT S.A., A CORP. OF BELGIUM (BE) 1985-06-25 US disclosed
EP-0118941-A1 Steel fibre reinforced rubber article N.V. BEKAERT S.A. (BE) 1984-09-19 EP disclosed
US-4396052-A SANDWICH LAYER OF VULCANIZED BLENDS OF 1,3-BUTADIENE-METHYLALLENE POLYMER AND NATURAL RUBBER OR POLYISOPRENE THE YOKOHAMA RUBBER CO., LTD. (JP) 1983-08-02 US disclosed
US-4347290-A HAVING AN ADHESIVE COATING OF A BRASS ALLOY CONTAINING COBALT N.V. BEKAERT S.A. (BE) 1982-08-31 US disclosed
US-4255496-A Steel wire reinforcing elements with a brass-cobalt alloy adhesive coating N. V. BEKAERT S.A. (BE) 1981-03-10 US disclosed