Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 20/20 | 0.82 |
| ▸ | BCL2 | P10415 | 19/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL554012 | 0.95 | BCL2L1 (0.91) | BCL2L1BCL2 | |
| SCHEMBL554010 | 0.95 | BCL2L1 (0.91) | BCL2L1BCL2 | |
| SCHEMBL554011 | 0.95 | BCL2L1 (0.91) | BCL2L1BCL2 | |
| SCHEMBL571152 | 0.95 | BCL2L1 (0.82) | BCL2L1BCL2 | |
| SCHEMBL10225728 | 0.91 | BCL2L1 (0.90) | BCL2L1BCL2 | |
| SCHEMBL554900 | 0.90 | BCL2L1 (1.00) | BCL2L1BCL2 | |
| SCHEMBL553479 | 0.90 | BCL2L1 (1.00) | BCL2L1BCL2 | |
| SCHEMBL554501 | 0.90 | BCL2L1 (1.00) | BCL2L1BCL2 | |
| SCHEMBL555059 | 0.90 | BCL2L1 (1.00) | BCL2L1BCL2 | |
| SCHEMBL554500 | 0.90 | BCL2L1 (1.00) | BCL2L1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601177-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | AstraZeneca AB (SE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017251-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ASTRAZENECA AB (SE) | 2012-02-09 | — | — | WO | disclosed |