SCHEMBL5715671

SCHEMBL5715671

CCCCCCCCCNCCC.Fc1ccc(-c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
SIGMAR1 Q99720 1/20 0.37
HRH4 Q9H3N8 4/20 0.35
HRH3 Q9Y5N1 4/20 0.35
LMNA P02545 1/20 0.35
S1PR2 O95136 1/20 0.34
S1PR1 P21453 1/20 0.34
S1PR3 Q99500 1/20 0.34
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
CHRM2 P08172 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5716247 0.97 EPHX2 (0.46) EPHX2SMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL5716446 0.95 EPHX2 (0.45) EPHX2SMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL5716452 0.94 EPHX2 (0.37) EPHX2SMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL5716005 0.91 EPHX2 (0.38) EPHX2SMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL5715753 0.90 EPHX2 (0.43) EPHX2SMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL5715944 0.86 EPHX2 (0.38) EPHX2SMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL5716271 0.85 TSHR (0.44) EPHX2SMN1; SMN2MEN1KMT2ATSHR
SCHEMBL5715863 0.84 EPHX2 (0.33) EPHX2
SCHEMBL6439619 0.84 EPHX2 (0.36) EPHX2SMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL5716022 0.83 EPHX2 (0.38) EPHX2SMN1; SMN2MEN1KMT2AHRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed
EP-1252166-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2002-10-30 EP disclosed
WO-2001042249-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed