Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5715944 | 0.99 | EPHX2 (0.38) | EPHX2ALDH1A1TSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL5715770 | 0.94 | ALDH1A1 (0.35) | EPHX2ALDH1A1TSHRCYP3A4KDM4E | |
| SCHEMBL5715913 | 0.91 | ALDH1A1 (0.35) | EPHX2ALDH1A1TSHRCYP3A4KDM4E | |
| SCHEMBL5715951 | 0.90 | ALDH1A1 (0.34) | EPHX2ALDH1A1TSHRCYP3A4KDM4E | |
| SCHEMBL5716247 | 0.87 | EPHX2 (0.46) | EPHX2ALDH1A1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL5716446 | 0.85 | EPHX2 (0.45) | EPHX2ALDH1A1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL5715671 | 0.84 | EPHX2 (0.44) | EPHX2ALDH1A1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL5716005 | 0.84 | EPHX2 (0.38) | EPHX2ALDH1A1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL6460674 | 0.83 | ALDH1A1 (0.40) | ALDH1A1TSHRCYP3A4KDM4ELMNA | |
| SCHEMBL5715757 | 0.82 | EPHX2 (0.35) | EPHX2SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252166-B1 | OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM | EXXONMOBIL CHEM PATENTS INC (US) | 2005-11-09 | — | — | EP | disclosed |