Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1789331 | 0.77 | — | — | |
| SCHEMBL1691719 | 0.72 | — | — | |
| SCHEMBL15206829 | 0.69 | — | — | |
| SCHEMBL16935145 | 0.69 | CES2 (0.39) | TSHRCES2CES1KEAP1MAPT | |
| SCHEMBL1309059 | 0.69 | — | — | |
| SCHEMBL1384962 | 0.67 | TSHR (0.57) | TSHRCES2CES1KEAP1MAPT | |
| SCHEMBL1305502 | 0.66 | CES2 (0.45) | TSHRCES2CES1KEAP1MAPT | |
| SCHEMBL22485690 | 0.66 | CES2 (0.45) | TSHRCES2CES1KEAP1MAPT | |
| SCHEMBL1588235 | 0.65 | CES2 (0.41) | TSHRCES2CES1KEAP1MAPT | |
| SCHEMBL28638097 | 0.65 | HSD17B2 (0.38) | TSHRCES2CES1KEAP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329477-B1 | Polythiophenes and devices thereof | XEROX CORP (US) | 2006-08-09 | — | — | EP | disclosed |