SCHEMBL5715871

SCHEMBL5715871

CCCCCCN(CC)c1cc(F)c(F)c(C(F)(F)C(F)(F)F)c1F

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6442430 1.00 CYP3A4 (0.33) CYP3A4MAPTMAPK1
SCHEMBL5715818 0.94
SCHEMBL5716309 0.91
SCHEMBL5716101 0.91
SCHEMBL5716134 0.89 CYP3A4 (0.36) CYP3A4MAPTMAPK1
SCHEMBL5716037 0.89 IGLV6-57 (0.30) CYP3A4MAPK1
SCHEMBL6786162 0.86 NR1H2 (0.32) CYP3A4MAPTMAPK1
SCHEMBL6791569 0.85 NR1H2 (0.31) CYP3A4MAPTMAPK1
SCHEMBL5715914 0.85 GPR84 (0.34)
SCHEMBL5715816 0.84 KDM4E (0.34) CYP3A4MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed
EP-1252166-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2002-10-30 EP disclosed
WO-2001042249-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed