Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5715915 | 1.00 | NPC1 (0.53) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL4883234 | 0.92 | ALDH1A1 (0.54) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL4883238 | 0.92 | ALDH1A1 (0.54) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL4878977 | 0.91 | MAPT (0.59) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL4890089 | 0.91 | POLB (0.61) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL4887969 | 0.91 | KMT2A (0.61) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL4886157 | 0.91 | POLB (0.61) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL4886161 | 0.91 | POLB (0.61) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL4883205 | 0.91 | KMT2A (0.61) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL4883211 | 0.91 | KMT2A (0.61) | NPC1RAB9AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725227-A1 | USE OF NEW LIPOXYGENASE INHIBITORS | Biolipox AB (SE) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005084656-A1 | USE OF NEW LIPOXYGENASE INHIBITORS | BIOLIPOX AB (SE) | 2005-09-15 | — | — | WO | disclosed |