Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | MITF | O75030 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.47 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571974 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTTDP1THRBPTPN1 | |
| SCHEMBL15695046 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTTDP1THRBPTPN1 | |
| SCHEMBL17296068 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTTDP1THRBPTPN1 | |
| SCHEMBL571286 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTTDP1THRBPTPN1 | |
| SCHEMBL571040 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTTDP1THRBPTPN1 | |
| SCHEMBL572045 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTTDP1THRBPTPN1 | |
| SCHEMBL572005 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTTDP1THRBPTPN1 | |
| SCHEMBL571017 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTTDP1THRBPTPN1 | |
| SCHEMBL572109 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTTDP1THRBPTPN1 | |
| SCHEMBL571081 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTTDP1THRBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015183985-A2 | THERAPEUTIC COMPOSITIONS INCLUDING NAPHTHOQUINONES AND USES THEREOF | STEALTH PEPTIDES INTERNATIONAL, INC. (MC) | 2015-12-03 | — | — | WO | disclosed |
| EP-2600857-A2 | TREATMENT OF MITOCHONDRIAL DISEASES WITH NAPHTHOQUINONES | Edison Pharmaceuticals, Inc. (US) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012019029-A2 | TREATMENT OF MITOCHONDRIAL DISEASES WITH NAPHTHOQUINONES | EDISON PHARMACEUTICALS, INC. (US) | 2012-02-09 | — | — | WO | disclosed |