Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5716626 | 1.00 | EPHX2 (0.57) | EPHX2NR1H4TRPV1 | |
| SCHEMBL5716408 | 0.83 | EPHX2 (0.68) | EPHX2NR1H4TRPV1 | |
| SCHEMBL5716171 | 0.80 | TRPV1 (0.72) | EPHX2NR1H4TRPV1 | |
| SCHEMBL27632246 | 0.79 | NR1H4 (0.45) | EPHX2NR1H4 | |
| SCHEMBL5827254 | 0.77 | EPHX2 (0.74) | EPHX2NR1H4TRPV1 | |
| SCHEMBL5147522 | 0.76 | TRPV1 (0.63) | EPHX2NR1H4TRPV1 | |
| SCHEMBL117355 | 0.76 | NR3C2 (0.67) | EPHX2NR1H4TRPV1 | |
| SCHEMBL12567953 | 0.75 | EPHX2 (0.80) | EPHX2NR1H4TRPV1 | |
| SCHEMBL5674452 | 0.75 | EPHX2 (0.54) | EPHX2NR1H4TRPV1 | |
| SCHEMBL5674449 | 0.73 | EPHX2 (0.52) | EPHX2NR1H4TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558574-A4 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | DIGITAL BIOTECH CO LTD (KR) | 2006-06-21 | — | — | EP | claimed |
| US-20050288369-A1 | Novel n-hydroxy thiourea, urea and amide compounds and the pharmaceutical compositions comprising the same | DIGITAL BIOTECH CO., LTD. (KR) | 2005-12-29 | — | — | US | claimed |
| EP-1558574-A1 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Digital Biotech Co., Ltd. (KR) | 2005-08-03 | — | — | EP | claimed |
| WO-2004035533-A1 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | DIGITAL BIOTECH CO., LTD. (KR) | 2004-04-29 | — | — | WO | claimed |
| EP-1558574-A4 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | DIGITAL BIOTECH CO LTD (KR) | 2006-06-21 | — | — | EP | disclosed |
| US-20050288369-A1 | Novel n-hydroxy thiourea, urea and amide compounds and the pharmaceutical compositions comprising the same | DIGITAL BIOTECH CO., LTD. (KR) | 2005-12-29 | — | — | US | disclosed |
| EP-1558574-A1 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Digital Biotech Co., Ltd. (KR) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004035533-A1 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | DIGITAL BIOTECH CO., LTD. (KR) | 2004-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288369-A1 | Novel n-hydroxy thiourea, urea and amide compounds and the pharmaceutical compositions comprising the same | HRH2, HRH4, NMUR2 | EPHX2 2053/4885NR1H4 467/4885TRPV1 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.