SCHEMBL571618

SCHEMBL571618

CCNN1C(=O)C(=Cc2ccccc2)SC1=S

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 1/20 0.66
▸ CISD1 Q9NZ45 4/20 0.61
▸ MAOA P21397 2/20 0.61
▸ MAOB P27338 1/20 0.61
▸ KMT2A Q03164 9/20 0.59
▸ MEN1 O00255 7/20 0.59
▸ MAPT P10636 5/20 0.59
▸ KDM4E B2RXH2 2/20 0.59
▸ ALDH1A1 P00352 1/20 0.59
▸ HPGD P15428 1/20 0.59
▸ GAA P10253 1/20 0.56
▸ TDP1 Q9NUW8 1/20 0.56
▸ CRHBP P24387 1/20 0.53
▸ CRHR2 Q13324 1/20 0.53
▸ ATM Q13315 1/20 0.53
▸ POLB P06746 1/20 0.53
▸ NPSR1 Q6W5P4 1/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.52
▸ RECQL P46063 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24129903 0.78 CISD1 (0.67) CISD1MAOAMAOBKMT2AMEN1
SCHEMBL2447131 0.78 CISD1 (0.67) CISD1MAOAMAOBKMT2AMEN1
SCHEMBL2447134 0.78 CISD1 (0.67) CISD1MAOAMAOBKMT2AMEN1
SCHEMBL10715160 0.77 MAOA (0.75) CISD1MAOAMAOBKMT2AMEN1
SCHEMBL10487963 0.77 MAOA (0.75) CISD1MAOAMAOBKMT2AMEN1
SCHEMBL11778921 0.76 CISD1 (1.00) CISD1MAOAMAOBKMT2AMEN1
SCHEMBL12333891 0.76 CISD1 (1.00) CISD1MAOAMAOBKMT2AMEN1
SCHEMBL10801539 0.76 CISD1 (1.00) CISD1MAOAMAOBKMT2AMEN1
SCHEMBL6906446 0.76 KMT2A (0.86) PKMKMT2AMEN1MAPTCRHBP
SCHEMBL6906444 0.76 KMT2A (0.86) PKMKMT2AMEN1MAPTCRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9999217-B2 Compositions for stabilizing DNA, RNA, and proteins in blood and other biological samples during shipping and storage at ambient temperatures BIOMATRICA, INC. (US) 2018-06-19 — — US disclosed
US-20160338342-A1 COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES EXACT SCIENCES CORPORATION 2016-11-24 — — US disclosed
EP-2598661-A2 COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN SALIVA AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES Biomatrica, INC. (US) 2013-06-05 — — EP disclosed
EP-2598660-A2 COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES Biomatrica, INC. (US) 2013-06-05 — — EP disclosed
WO-2012018639-A2 COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN SALIVA AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES BIOMATRICA, INC. (US) 2012-02-09 — — WO disclosed
WO-2012018638-A2 COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES BIOMATRICA, INC. (US) 2012-02-09 — — WO disclosed
CN-101628238-A Ultrahigh-temperature ammonia decomposition catalyzer for coke oven gas and preparation method thereof WUXI CITY QIANGYA REFRACTORY M 2010-01-20 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160338342-A1 COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES HNRNPD, HNRNPDL, HNRNPL PKM 2830/4885CISD1 2858/4885MAOA 4339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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