SCHEMBL5716192

SCHEMBL5716192

CCCCCCNC(F)(F)C(F)(F)F.Fc1ccc(-c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.40
MLYCD O95822 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
RORA P35398 1/20 0.31
RORC P51449 1/20 0.31
NR1H4 Q96RI1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5716529 0.87 EPHX2 (0.37) EPHX2
SCHEMBL5715859 0.84 EPHX2 (0.34) EPHX2
SCHEMBL5716247 0.83 EPHX2 (0.46) EPHX2MEN1KMT2ASMN1; SMN2
SCHEMBL5715802 0.83 EPHX1 (0.37) EPHX2MLYCD
SCHEMBL5716446 0.82 EPHX2 (0.45) EPHX2MEN1KMT2ASMN1; SMN2
SCHEMBL5715671 0.81 EPHX2 (0.44) EPHX2MEN1KMT2ASMN1; SMN2
SCHEMBL5715753 0.80 EPHX2 (0.43) EPHX2MEN1KMT2ASMN1; SMN2
SCHEMBL5716005 0.77 EPHX2 (0.38) EPHX2MEN1KMT2ASMN1; SMN2
SCHEMBL5715763 0.77
SCHEMBL5715557 0.76 TLR8 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed